John Lyon's botany journal offers a record of travels in the eastern U.S. at the turn of nineteenth century. The volume includes memoranda dated 1799, with entries spanning 9/6/1802-8/6/1814. Lyon's entries document expenses—plants purchased and collected—with occasional notes about the places and peoples he encounters. Entries related to his travels in the eastern and southeastern U.S. record a visit to plantations (4/23/1803), an Indian settlement in Georgia (7/19/1803), and medical treatments for palsy, jaundice, and cancer (12/1/1808). Notably, Lyon discusses an albino slave in Athens, Georgia, as excerpted in Selected Quotations (9/25/1804). In the spring of 1806, he records travel to Dublin, Liverpool, and London. Thus, while the Lyon journal will certainly appeal to researchers exploring nineteenth century botany, they also feature content with wider appeal, such as U.S. slavery, transatlantic travel, indigenous trade, and antebellum medicine.
 

The journal was printed in APS Proceedings 26 (1889):1. The Kentucky travels can be found in Reuben G. Thwaites' Early Western Travels, 1748-1846.

Michaux maintained travel journals during his excursions throughout North America between 1787-1796. These 10 volumes furnish accounts of Charleston (September 1787), Saint Augustine and the Bahamas (1787-88), the Savannah River (December 1788), and Kentucky shortly after statehood (1794-95). Notably, Michaux records at least one visit to David Rittenhouse and Thomas Jefferson (12/14/1793), and he makes a proposal to the American Philosophical Society to explore unknown regions beyond Missouri and Kentucky, which Jefferson, then Secretary of State, accepts (12/10/1792). French-reading researchers—the volumes are maintained entirely in French—ought to find that these volumes offer insights into Southern and Western exploration during the early national period.
 
The journal was printed in APS Proceedings 26 (1889):1. The Kentucky travels can be found in Reuben G. Thwaites' Early Western Travels, 1748-1846.