Between 1764 and 1781, the Scots surveyor George Gauld was assigned by the British Admirality to chart the waters of the Gulf Coast off British West Florida, an area that extended from New Orleans to the modern-day Florida. In 1773, Gauld submitted some of his findings to the APS, probably in hopes of having them published in the Transactions, and although these were not published, they became one of the first mansucripts entered into the Society's collections. Contains occasional brief references to Native peoples of the areas described. The Gauld manuscript also includes an extract of a letter from John Lorimer to Gauld, 1772, and a sketch of the Middle and Yellow Rivers of West Florida by Thomas Hutchins. When it was received at the APS, it was endorsed: "This long uninteresting Paper can hardly obtain a Place in the Transactions of a Philosophical Society. It should however be preserved in the Files for the Use of Historians or map makers."

Consists of material chiefly on natural history, shells, and insects, including miscellaneous notes on conchology by Say; photostats of 6 letters from Say to Jacob Gilliams, 1819-1829, from Morristown, New Jersey; and a biographical note on Say. The drawings and impressions of shells are by Mrs. Lucy Way Sistaire Say, prepared for W. G. Binney's edition of Say's complete works on conchology, 1858; also Mrs. Say's refutation of what she considered an unfair attack in George Ord's memoir of Say. Correspondents include André Etienne Férussac, Arthur F. Gray, John Lawrence LeConte, and Charles W. Short. An additional item is a memorial volume (ca. 150 pp.), including a family genealogy and land surveys in watercolor (B Sa95f).

Correspondence from Charles Mason and Jeremiah Dixon to Thomas Birch, and Nevil Maskelyne to Charles Mason, relating to the survey, and the transits of Venus (1761,1769).

A compendium of natural philosophical knowledge, written in 1718-1720 by John Questebrune, chaplain to the 6th Earl of Galway. The chapters treat the various parts of the physical world (earth, water, air, and fire), plants (including a great deal on medicinal plants), animals, and the human body and soul. The volume is embellished with decorative chapter headings and pen and ink and watercolor sketches depicting the terrestrial globe, the Ptolemaic and Copernican solar systems, the phases of the moon, and the human body in dissection.

Letters (including some transcripts and photostats) from and to Vaughan from many American and British correspondents, including: Also personal correspondence and business papers of Benjamin, Charles, Petty, Samuel Sr., Samuel Jr., William, William Oliver, and Sarah Vaughan (2 boxes); lectures, mostly in shorthand (3 vols.); a large number of notes and memoranda on a wide variety of topics, such as agriculture, architecture, astronomy, diplomacy, diseases, dueling, electricity, hieroglyphs, internal improvements, medicine, meteorology, land, manufactures, politics, punctuation, religion, silk-manufacturing, stock-breeding, taxation, Unitarianism, Benjamin Franklin, John Locke, Napoleon I, Joseph Priestley, Bowdoin College, town of Hallowell, Maine; notes on the peace negotiations, 1782-1783; miscellaneous legal papers; genealogy of the Abbott-Vaughan families. For a personal account of the collection, see Mrs. Mary Vaughan Marvin, "The Benjamin Vaughan Papers," APS Proceedings 95 (1951): 246-249.