Physician John Wakefield Francis (1789-1861) cofounded the New York Academy of Medicine. He served as the second president of the Academy, taught at Bellevue Hospital, wrote medical texts, and edited professional journals. Collection consists of correspondence, financial papers, writings, by-laws and minutes, and related papers of Francis and others. Correspondence of others include letters to Francis's associates and family members. Financial documents, 1798-1851, are accounts, receipts, receipt books, checks, and collection notices. Writings are speeches, lectures and notes of Francis and others. Also, minutes and by-laws, 1807-1810, of the Medical and Surgical Society of the University of New York State; and printed material.

These letters and papers include a memorandum book (1795-1827), lectures on botany and medicine, genealogical materials, committee reports from Columbia College, speeches, minutes of the New York Horticultural Society (1822-1828), letters to Sir James Edward Smith (1817-1826), a receipt book of Alexander Hosack (1781-1801), and diaries of Thomas K. Wharton (1830-1862).

Edward Uhler Condon was a theoretical physicist at Princeton University and Westinghouse Laboratories who later served as director of the National Bureau of Standards (1945-1951), and as the director of research and development (1951-1954) and consulting physicist (1954-1974) at Corning Glass Works. The Condon Papers includes correspondence, notebooks, writings, photographs, and other materials concerning Condon's education, teaching, and his government, industrial, and academic.