This collection includes letters, deeds, receipts. There are several letters concerning the ordering and delivery of scales and weights to various banks, including the Farmers Bank of Virginia, and the U.S. Bank in Savannah, Georgia. There are numerous documents relating to the Voights, namely deeds, real estate transactions, and indenture contracts. There is also a copy of a letter from Elias Boudinot of the U.S. Mint in Philadelphia concerning directions for closing the Mint in case of a yellow fever outbreak (1803).

This collection contains minutes of the Society, 1781-1975; minutes of the directors of the Corporation, 1929-1947; membership book (with signatures of early members), 1785; and names of later members. There are also deeds to the meeting house and burying ground; treasurers' accounts; reports of officers and committees; bills and receipts for constructing, maintaining, and repairing the meeting house; cancelled checks; and letters to the Society and its officers, especially Samuel Wetherill, 1883-1884.

One of the oldest houses in Philadelphia, Wyck is now a non-profit museum listed on the National Register of Historic Places. Nine generations of the Jansen-Wistar-Haines family owned the Wyck property from 1690 until 1973. The last family owner deeded 2.5 acres of land, the house and its contents, several outbuildings, a landscaped garden, and a small endowment to the Wyck Charitable Trust. The Wyck Charitable Trust and the Wyck Association now administer the preservation of the property and its educational services to the public. This collection contains diaries, letters, accounts, bills and receipts, deeds, and photographs. The collection as a whole is deepest for the period 1770-1970. Items of particular note include accounts of household expenses at Wyck from ca. 1790-1970; papers pertaining to the Academy of Natural Sciences of Philadelphia, Quaker schools, and social reform groups; agricultural and horticultural practices; and correspondence to and from cultural leaders of 18th and 19th century Philadelphia. The papers of the John S. Haines family (Ms. Coll. 52A) form part of the Wyck Papers. The papers cover the years 1845 to 1949 and are arranged into eight series.