Sarah Franklin Bache (1743-1808), a Revolutionary War patriot and daughter of Benjamin Franklin, led an active public life according to the standards of womanhood in the late eighteenth century. As the daughter of Benjamin Franklin she had an unusual access, for a woman, to the political life in revolutionary Philadelphia. Although her primary role was of caretaker of her family and home, Bache played an active role in the Revolution through her relief work and as her father's political hostess. The Sarah Franklin Bache papers consist of incoming and outgoing correspondence ranging from 1768 to 1807 mostly of a personal nature to and from friends and relatives. The correspondence of her relatives includes her nephew William Temple Franklin, her brother William Franklin and her children.

The Smith-Houston-Morris-Ogden Family Papers document the history of the Houston, Smith, Ogden, Morris and allied families, beginning in the late 17th century, and continuing through to near the end of the 20th. Among the many treasures in this vast collection are the papers of Pennsylvania Railroad executive Henry Howard Houston (1820-1895), his son, Samuel Frederick Houston (1866-1952), and of Pennsylvania attorney and treasury official, William Meredith (1752-1816). Although the collection contains a great deal of interest with respect to land speculation, commerce, and trade emanating from Philadelphia, the bulk of the Smith Family Papers consists of personal and family correspondence and other papers. Among the largest and most interesting bodies of papers are those of L.M.C. Smith and Eleanor Houston Smith, daughter of Samuel F. Smith. These document the family's progressive attitudes regarding and resource conservation, historic preservation, and their social activism. This very large collection includes much material that is not itemized below.