Meriwether Lewis and William Clark were explorers. This collection contains the manuscript journals kept by Lewis and Clark on their travels to the source of the Missouri River and across the continent to the Pacific Ocean. There are interlineations throughout by Nicholas Biddle, who published his narrative "History of the Expedition of Captains Lewis and Clark" (1814).

Robert Woodruff was secretary to John Anstey, Loyalists' Claims Commissioner. This journal relates his travels with John Anstey. He describes the towns he visited, and comments on episodes of the American Revolution and on the Federal Convention and state ratifying conventions. The journal covers a trip through New York, New Jersey, Pennsylvania, Delaware, Maryland, Virginia, North Carolina, Rhode Island, Massachusetts, South Carolina and Georgia. He and Anstey spent a night at Mount Vernon in 1786. Mentions B. Franklin, G. Washington, APS Hall. Also refers to Five Nations country, Georgia's warfare with Creek Indians, and Chief McGillivray. For identification, see G. Washington's Diary, Dec.11, 1786.

This item contains entries about prominent people (primarily accounts of their deaths); Philadelphia events and gossip; the Pennsylvania Hospital; questions for Meriwether Lewis on Indian physical history, medicine, morals, and religion; and his views on marriage, religion, physicians, etc. Also includes meeting with Captain Wells and Little Turtle; speculations on Indian skin color at the equator.

This autobiography relates Rush's experiences in college and medical school; his meetings with notable doctors; his life in Scotland, England, and France; his medical views; the military and politics during the Revolutionary War; and brief sketches of personalities of that period.