American Philosophical Society
Member History

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Resident (2)
2. Biological Sciences[X]
204. Medicine, Surgery, Pathology and Immunology[X]
1Name:  Dr. Richard John Bing
 Institution:  Huntington Medical Research Institutes & University of Southern California
 Year Elected:  1995
 Class:  2. Biological Sciences
 Subdivision:  204. Medicine, Surgery, Pathology and Immunology
 Residency:  Resident
 Living? :   Deceased
 Birth Date:  1909
 Death Date:  November 8, 2010
Richard J. Bing was born in Germany in 1909 and went on to become one of the great cardiologists of our time. In a career spanning more than sixty years, he pioneered the application of basic sciences to the study of the human heart. His early investigations were devoted to the mechanism of hypertension. He made seminal discoveries on the mechanism of congenital heart disease and of congestive heart failure by using physical and biochemical techniques and pioneered coincidence counting in the determination of coronary flow and in heart imaging. This work laid the foundation for modern PET scanning techniques. His investigation on cardiac metabolism showed that heart failure is related to possible defects in contractile proteins. Dr. Bing taught and conducted research at Johns Hopkins University and the University of Alabama and was chairman of medicine at Washington University's Veterans Administration Hospital. In 1959 he became chairman of the Department of Medicine at Wayne State University and in 1969 he was appointed professor of medicine at the University of Southern California. He joined Huntington Medical Research Institutes in 1969 to do biomedical research and also started the internal medicine residency program at Huntington Hospital. His major achievements there have included high-speed cinematography of coronary vessels and studies of the chemistry of the heart after a heart attack. Dr. Bing also followed a highly successful second career as a distinguished musician and composer. His chamber music has been performed by professional ensembles including the Chamber Players of the Los Angeles Philharmonic. His Mass had its premier performance by the Vienna Philharmonic at St. Stephen's Cathedral in Vienna in 1993. Richard John Bing died on November 8, 2010, at the age of 101, at his home in the Los Angeles-area community of La Canada Flintridge.
2Name:  Dr. Bert Vogelstein
 Institution:  Howard Hughes Medical Institute & Johns Hopkins Oncology Center
 Year Elected:  1995
 Class:  2. Biological Sciences
 Subdivision:  204. Medicine, Surgery, Pathology and Immunology
 Residency:  Resident
 Living? :   Living
 Birth Date:  1949
Bert Vogelstein stands out among the leading contemporary workers in the field of the molecular genetic basis of cancer, with his work in the area of colorectal cancer of particular note. He has effectively proven the multi-step process of carcinogenesis from benign adenoma to metastasizing cancer, and he identified mutations in the APC gene as an early and very frequent change in sporadic colon cancer as well as a constitutional change in persons with familial polyps of the colon. He was also responsible for defining a new type of cancer-producing gene mutation, mapping to chromosome 2, in familial colon cancer, and for identifying a specific oncogene in gliomas (brain tumors). Dr. Vogelstein's contributions are of the greatest importance for understanding the progression of malignancy, for early diagnosis of cancer, and for prevention of cancer. Currently Clayton Professor of Oncology at the Johns Hopkins Oncology Center as well as an investigator at the Howard Hughes Medical Institute, he has been affiliated with Johns Hopkins University since receiving his Ph.D. from that institution in 1974. Dr. Vogelstein's many awards include the Alison Eberlein Award for Outstanding Contributions to Leukemia Research (1968), the Gairdner Foundation International Award in Science (1992), the American Cancer Society's Medal of Honor (1992), the Richard Lounsbery Award of the National Academy of Sciences, to whose membership he was elected in 1992, the Charles Rodophe Brupbacher Prize for Cancer Research (2012), the Breakthrough Prize in Life Sciences (2013), the Dr. Paul Janssen Award for Biomedical Research (2015),and the Gruber Genetics Prize (2019). He is also a member of the National Cancer Institute and the American Academy of Arts & Sciences.
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