American Philosophical Society
Member History

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2. Biological Sciences[X]
201. Molecular Biology and Biochemistry[X]
1Name:  Dr. David Botstein
 Institution:  Princeton University; Calico
 Year Elected:  2008
 Class:  2. Biological Sciences
 Subdivision:  201. Molecular Biology and Biochemistry
 Residency:  Resident
 Living? :   Living
 Birth Date:  1944
In 2013 David Botstein retired as the Director of the Lewis-Sigler Institute for Integrative Genomics at Princeton University and joined Calico as Chief Scientific Officer. Calico is a Google startup that will focus on aging and life-extension. Previously he served as Griswold Professor of Genetics at the Massachusetts Institute of Technology; as vice president of science for Genentech, Inc.; and as Acherman Professor and chairman of the Department of Genetics at the Stanford University School of Medicine. A native of Switzerland, he holds a Ph.D. from the University of Michigan (1967). David Botstein is one of the greatest geneticists working today and a pioneer in more ways than one. His early genetic work contributed to the discovery and understanding of transposable elements in bacteria. In the 1970s, his studies were instrumental in making the yeast Saccharomyces cerevisiae a major model organism that continues to be prominent in both fundamental biological research and biotechnology. A seminal 1980 paper by Botstein and colleagues suggested to employ restriction fragment length polymorphisms (RFLPs) for producing a linkage map of the human genome. That visionary proposal became the foundation of the new science of genomics. He also co-founded the Saccharomyces Genome Database, which continues to be a leading international resource that connects genomic sequences with biological functions. In addition, Botstein is a pioneering educator who revamped the Princeton biological curriculum through the teaching of biology in close juxtaposition to physics, mathematics and chemistry. David Botstein is a member of the National Academy of Sciences (1981); the American Academy of Arts & Sciences (1985); and the Institute of Medicine (1993). Other professional honors include the Eli Lilly Award (1978); the Genetics Society of America Medal (1988); the Rosenstiel Award (1992); the Gruber Prize in Genetics (2003); and the Breakthrough Prize in Life Sciences (2013). David Botstein was elected a member of the American Philosophical Society in 2008.
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