Subdivision
| • | 102. Chemistry and Chemical Biochemistry | [X] |
| | 1 | Name: | Dr. John I. Brauman | | | Institution: | Stanford University | | | Year Elected: | 2004 | | | Class: | 1. Mathematical and Physical Sciences | | | Subdivision: | 102. Chemistry and Chemical Biochemistry | | | Residency: | Resident | | | Living? : |
Deceased
| | | Birth Date: | 1937 | | | Death Date: | 08/23/2024 | | | | | | |
John I. Brauman earned a Ph.D. from the University of California, Berkeley in 1963 and joined the faculty at Stanford University later that year. He was named J. G. Jackson-C. J. Wood Professor of Chemistry in 1972, and since 1999 he has also served as Cognizant Dean for Natural Sciences at Stanford. Dr. Brauman was the first to show that the relative order of acidities and basicities of many simple organic compounds are reversed between gas phase and solution. He was then able to rationalize both the gas-phase and solution behavior and put them on a much more substantial footing. Dr. Brauman discovered a wealth of information about the dynamics of gas-phase ionic reactions, which again has revolutionized scientific thought. Dr. Brauman was the first to measure accurate electron affinities of molecules larger than diatomics, eventually determining these important quantities for a substantial number of chemically interesting important organic radicals. He has received the American Chemical Society's Award in Pure Chemistry in 1973, the Arthur C. Cope Scholar Award (1986) and the James Flack Norris Award in Physical-Organic Chemistry (1986). Recent honors include the National Academy of Sciences Award in the Chemical Sciences (2001), the Linus Pauling Medal (2002) and the J. Willard Gibbs Medal (2003). Dr. Brauman was elected to the National Academy of Sciences and the American Academy of Arts & Sciences in 1976. | |
| 2 | Name: | Dr. JoAnne Stubbe | | | Institution: | Massachusetts Institute of Technology | | | Year Elected: | 2004 | | | Class: | 1. Mathematical and Physical Sciences | | | Subdivision: | 102. Chemistry and Chemical Biochemistry | | | Residency: | Resident | | | Living? : |
Living
| | | Birth Date: | 1946 | | | | | | |
JoAnne Stubbe is one of the world's leading enzymologists. Her specific interest is in how reactive chemical intermediates such as free radicals are exploited and controlled in biochemical processes to effect difficult chemical transformations. With experiments of sparkling originality, she showed that a key enzyme, ribonucleotide reductase, that is involved in the synthesis of deoxynucleotides, initiates its chemistry through an unusual diferrictyrosyl radical that abstracts a key hydrogen from the sugar nucleus. Surprisingly, an important chemotherapeutic agent, bleomycin, was shown by Dr. Stubbe to owe its antitumor activity to a free radical mechanism that neatly explains its chemical and sequence specificity. Currently Novartis Professor of Chemistry and Biology at the Massachusetts Institute of Technology, Dr. Stubbe has previously held faculty positions at Williams College (1972-77), Yale University Medical School (1977-80) and the University of Wisconsin (1980-87). She holds a Ph.D. from the University of California, Berkeley (1971). The recipient of honors including the Pfizer Award in Enzyme Chemistry (1986), the Alfred Bader Award in Bioorganic & Bioinorganic Chemistry (1997), the National Medal of Science (2009), and the Franklin Institute's Benjamin Franklin Medal in Life Science (2009). Dr. Stubbe was elected a member of the American Academy of Arts & Sciences in 1991 and the National Academy of Sciences in 1992. | |
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