| 1 | Name: | Dr. Paul Berg | |
| Institution: | Stanford University | ||
| Year Elected: | 1983 | ||
| Class: | 2. Biological Sciences | ||
| Subdivision: | 201. Molecular Biology and Biochemistry | ||
| Residency: | Resident | ||
| Living? : | Deceased | ||
| Birth Date: | 1926 | ||
| Death Date: | February 15, 2023 | ||
Paul Berg is an acknowledged leader in the study of gene transfer from bacteria to viruses to cells of higher organisms. He witnessed firsthand the history of recombinant DNA research and regulation, having been in the forefront of both movements since he was a young man. He became a professor of biochemistry at Stanford University School of Medicine in 1959, when he was 33. He was elected to the National Academy of Sciences before the age of 40, and he gained early recognition and influence when he delineated the key steps in which DNA produces proteins. Dr. Berg was awarded the Nobel Prize for Chemistry in 1980 for his work with DNA. In the mid-1970s, the National Academy of Sciences asked him to explore the safety of recombinant DNA technology. He responded with the historic "Berg letter," calling for a moratorium on recombinant DNA research until safety issues could be addressed. He was one of the key organizers of the international forum on recombinant DNA technology, the Asilomar Conference, which took place in February of 1975. One hundred leading scientists met at the conference to discuss the potential risks of gene-splicing experiments. The ensuing dialogue resulted in the National Institutes of Health (NIH) guidelines published a year later, a milestone of responsible self-regulation in science. Dr. Berg's laboratory continued to work with recombinant DNA techniques throughout the 1980s. In 1985, he became director of the New Beckman Center for Molecular and Genetic Medicine. In 1991, Dr. Berg was named head of the NIH's influential Human Genome Project. | |||