Francis John Worsley Roughton Papers

Mss.B.R755

Date: 1908-1972 | Size: 71 Linear feet

Abstract

This collection of correspondence and documents focuses on Roughton's prolific life's work on respiratory physiology. His specific work at Cambridge University from the 1920s to the 1960s, as well as interludes in the U. S. during World War II, are covered, as is the scientific milieu in which he worked. Some of the subjects or organizations for which there are documents, are: Bermuda and Naples Zoological Research Stations; British Glue and Gelatin Research Assoc.; Biochemical Journal; Cambridge Philosophical Society; Cambridge University Departments of Physiology (pre-1939) and Colloid Science (post-1940); Harvard Fatique Lab.; Medical research Council; Trinity College Cambridge.

Background note

Francis John Worsley Roughton was born June 6, 1899, son of John Paul Roughton. His father was the last of a dynasty of five generations who were all physicians. Francis entered Winchester College with the intention of following in the family tradition. From there he obtained a scholarship in mathematics and natural sciences to Trinity College, Cambridge. After studying physics, chemistry and physiology, he discovered his inclination for research.

In 1923 he became a fellow of Trinity College and in one or another category held a Fellowship at that college for the rest of his life. In the same year, he became a Cambridge University Lecturer in Biochemistry, but four years later moved to the Department of Physiology, lecturing on the physico-chemical aspects of that subject, especially blood and respiration. He joined Dr. E.D. Adrian in the direction of the medical studies. The pattern of Roughton's life work in research was formed in the mid-twenties when with Dr. H.H. Hartridge he investigated by direct observation the rate of combination of the haemoglobin in the blood with gases, expecially oxygen and carbon monoxide.

The pursuit of problems involving the speed with which gases reacted with blood led Roughton in 1932 to a new discovery. In collaboration with N.U. Meldrum he found and studied the important enzyme carbonic anhydrase that speeds up the transformation between carbon dioxide and carbonic acid. For this and the earlier work Roughton was elected to the Royal Society in 1936.

He was co-editor of the Biochemical Journal from 1935-1941. Appointed as Visiting Research Fellow in War Science and Medicine at Harvard and Columbia University in 1941, he worked on problems in aviation medicine, the treatment of traumatic shock and other urgent questions of war medicine.

In 1947, Roughton was appointed the Plummer Chair of Colloid Science at the University of Cambridge, and held this position until retiring in 1966. During this time he directed a research department that covered a wide range of problems both in biological and physico-chemical aspects of colloid science, while continuing his researches on blood and respiration. After his retirement, this work was intensified with his time divided between Milan and California. Married in 1925 to Alice Hopkinson, a general practitioner and psychiatrist, they had two children. On April 26, 1972 at the age of 72 years, Francis John Worsley Roughton died in Cambridge.

Scope and content

The Francis John Worsley Roughton Papers (1908-1972) contain professional and personal correspondence, research notes, manuscripts of published and unpublished works by Roughton and others, and notebooks on the physiology of blood and the physical biochemistry of hemoglobin. Primarily papers from the Department of Colloid Science at the University of Cambridge, also represented are lectures and notes from the Harvard Fatigue Laboratory, the University of Pennsylvania, and Milan, Italy. A copious note keeper, his stray thoughts are jotted down throughout the collection.

The papers 142 boxes; 71 lin. ft. are divided into ten series: Series I. Correspondence, 1908-1972, 21 boxes, 10.5 lin. ft.; Series II. Organizations, Foundations, and Conferences, 1923-1972, 9 boxes, 4.5 lin. ft.; Series III. University of Cambridge, 1915-1972, 12 boxes, 6 lin. ft.; Series IV. Jack Henry Schulman Papers, 1946-1957, 2 boxes, 1 lin. ft.; Series V. Works by Roughton, 1920-1972, 21 boxes, 10.5 lin. ft.; Series VI. Works by Others, 1926-1971, 12 boxes, 6 lin. ft.; Series VII. Research notes, 1926-1972, 19 boxes, 9.5 lin. ft.; Series VIII. Notebooks and Card Files, 1912-1970, 28 boxes, 14 lin. ft.; Series IX. Printed Materials, 1920-1971, 16 boxes, 8 lin. ft.; Series X. Graphics, Undated, 2 boxes, 1 lin. ft.

Collection Information

Provenance

Presented by Dr. Alice Roughton, 1975.

Physiology, Biochemistry, and Biophysics Note

The researches of the British scientist Francis J. W. Roughton on the physiology of blood and the physical biochemistry of hemoglobin are part of an intellectual tradition which included the British physiologists Joseph Barcroft, J. S. and J. B. S. Haldane, and A. V. Hill. In fact, Barcroft's and Hill's influence on Roughton was akin to mentorship. During the 1920s Roughton worked at Cambridge University on problems of oxygen diffusion in the blood, studies for which he was appointed Lecturer in Physical Biochemistry and in Physico-Chemical Physiology.

Roughton's research during the next four decades generally followed out of his work in the 1920s. That is, his early studies on diffusion were later broadened to include chemical reaction processes, theoretical and experimental analyses of factors that determine the rates of penetration of oxygen and carbon monoxide into red blood cells, and the transport of carbon dioxide in the blood. His measurements of oxygen association curves were important in elucidating the action of hemoglobin. In 1946 Roughton became chairman of the Department of Colloid Science at Cambridge, a center for research on surface chemistry and biophysical chemistry.

Roughton developed a successful research program in England, but was happier in America, where he lectured and conducted research during his extended visits. He spent much of World War II in the United States working on war projects such as carbon monoxide shock and studies in aviation medicine at the Harvard Fatigue Laboratory and the Physiological Laboratory of Columbia's Medical School; he remained associated with military research on blood physiology well past the war. In the 1950s and 1960s he also spent several semesters at the University of Pennsylvania, working closely with his colleague (and former student) Britton Chance. Because of the close bonds that Roughton had with American science, his papers have been deposited at the APS.

This collection contains notebooks, drafts of papers, manuscripts, lecture notes, calculations, laboratory manuals, annotated books from Roughton's personal library, reprints, photographs, and correspondence. The papers document Roughton's research in Cambridge and America, his war activities, and broader aspects of physiology, biophysics, and physical biochemistry.

Additional Biographical Notes:

Britton Chance was educated first at the University of Pennsylvania, obtaining a doctorate in 1940. A two-year association with F. J. W. Roughton, a specialist in the biochemistry and biophysics of hemoglobin, culminated in 1942 in a second doctorate from Cambridge University. Chance returned to the University of Pennsylvania to become professor of biophysics and biochemistry and director of the Eldridge Reeves Johnson Foundation. Under his leadership, the Department of Biophysics and Physical Biochemistry became a world center for the study of cell metabolism.

During the 1940s, Chance's research program focused mainly on enzyme kinetics of peroxidases, physico-chemical studies that elucidated in minute detail the mechanisms of formation of enzyme-substrate complexes. Broadened in scope in the 1950s, the research included the study of phosphorylation mechanisms in mitochondria and cytochromes. In general, by introducing new biochemical methods, especially sensitive photometric techniques, Chance was able to explain various physiological states of cell metabolism in vivo.

Indexing Terms


Corporate Name(s)

  • Bermuda Zoological Research Station
  • British Gelatine and Glue Research Association
  • Cambridge Philosophical Society.
  • Harvard Fatigue Laboratory.
  • Medical Research Council (Great Britain)
  • Naples Zoological Research Station.
  • Trinity College (University of Cambridge)
  • University of Cambridge.
  • University of Pennsylvania

Personal Name(s)

  • Adam, Neil Kensington
  • Barcroft, Joseph, 1872-1947
  • Berger, Robert Lewis
  • Cannon, Walter B. (Walter Bradford), 1871-1945
  • Chance, Britton, 1913-2010
  • Comroe, Julius H. (Julius Hiram), 1911-1984
  • Edsall, John T. (John Tileston), 1902-2002
  • Fatt, Irving
  • Forster, Robert E., 1919-
  • Gibson, Q.H.
  • Haldane, J. B. S. (John Burdon Sanderson), 1892-1964
  • Hartridge, Hamilton, b. 1886
  • Harvey, William, 1578-1657
  • Henderson, Lawrence Joseph, 1878-1942
  • Hill, A. V. (Archibald Vivian)
  • Hopkins, Frederick Gowland, Sir, 1861-1947
  • Horvath, Steven
  • Kernohan, John C.
  • Krebs, Hans Adolf, Sir
  • Kreuzer, F. (Ferdinand), 1919-
  • Meldrum, Norman U. (Norman Urquhart), 1907-1933
  • Needham, Joseph, 1900-1995
  • Otis, Arthur B.
  • Pauling, Linus, 1901-1994
  • Perutz, Max F., 1914-2002
  • Rossi-Bernardi, Luigi
  • Roughton, Francis John Worsley
  • Rutherford, Ernest, 1871-1937
  • Scholander, Per Fredrik, 1905-1980
  • Smith, Malcolm Herbert, 1932-
  • Van Slyke, Donald Dexter, 1883-1971
  • Wyman, Jeffries, 1901-1995

Subject(s)

  • Biochemistry.
  • Carbon dioxide
  • Carbon monoxide
  • Hemoglobin
  • Medical sciences.
  • Oxygen
  • Physiology.
  • Respiratory organs.
  • Science publishing.


Detailed Inventory

 Series I. Correspondence
1908-1972 Box 1-21
 A
1939-1970 Box 1
 Academic Press, Inc
1948-1959 Box 1
 Adair, G.S.
1948-1949 Box 1
 Adam, N.K.
1953-1966 Box 1
 Adrain, E.D.
1944-1948 Box 1
 Aero Research Limited
1947-1951 Box 1
 Aeschlimann, J.A.
1947-1957 Box 1
 Ainsworth, Stanley
1959-1971 Box 1
 Alberty, Robert A.
1955-1960 Box 1
 Alexander, A.E.
1947-1956 Box 1
 _____, Alfred
1944-1945 Box 1
 Allen, T.H.
1950 Box 1
 Ambache, Nachman
1944 Box 1
 Amberson, William R.
1929-1950 Box 1
 Aney, Ruth
1953-1954 Box 1
 Anglo American Corporation of South Africa
1957-1960 Box 1
 Ansell, Brian
1946-1949 Box 1
 Anthony, E.H.
1955-1961 Box 1
 Antonini, Eraldo
1960-1966 Box 1
 Aranow, Doris J.
1943-1972 3 folders Box 1
 Archives of Biochemistry
1952, 1958 Box 1
 Armstrong, Bruce W.
1960 Box 1
 Army Air Forces
1944 Box 1
 Ashmore, P.G.
1960 Box 1
 Assali, N.S.
1963-1964 Box 1
 Astrup, Poul
1964-1971 Box 1
 Atchley, Floyd O.
1966 Box 1
 B
1936-1970 Box 2
 Baldwin, Eleanor
1945 Box 2
 Barcroft, Henry
1948-1963 Box 2
 Barcroft, Joseph
1920-1962 Box 2
 Barcroft, Lady
1948-1950 Box 2
 Barcroft, Robbie
1950 Box 2
 Barron, Charles H.
1969-1972 Box 2
 Barron, Donald H.
1947-1950 Box 2
 Bate-Smith, E.C.
1948-1966 Box 2
 Bates, D.V.
1950-1960 Box 2
 Bauer, Christian
1970-1972 Box 2
 Baumberger, J. Percy
1944-1948 Box 2
 Bayliss, L.E.
1959 Box 2
 Bazett, Cuthbert
1945 Box 2
 Beale, Evelyn
1936,1971 Box 2
 Beattie, John
1949-1950 Box 2
 Bebbington, John
1963-1966 Box 2
 Beddall, C.
1967-1968 Box 2
 Behnke, Albert
1940-1945 Box 2
 Bell, R.P.
1948 Box 2
 Benesch, Reinhold
1965-1970 Box 2
 Berger, Robert Lewis
1954-1972 2 folders Box 2
 Best, C.H.
1947 Box 2
 Biochemical Journal
1934-1970 4 folders Box 2

Regarding submission of papers, with some summaries of author's papers included.

Other Descriptive Information: See also: Biochemical Society

 Biochimica et Biophysica Acta
1969 Box 3
 Bishop, J.M.
1957-1958 Box 3
 Blackwell Scientific Publications
1948 Box 3
 Blair, G.W. Scott
1959 Box 3
 Blank, Martin
1957-1964 Box 3
 Bleusoraith, F.K.
1950 Box 3
 Blundell, P.H.
1960-1963 Box 3
 Boeri, Enzo
1948-1950 Box 3
 Booth, F.
1956 Box 3
 Boothby, Walter M.
1944-1953 Box 3
 Bracegirdle, B.M.
1960 Box 3
 Bragg, Lawrence
1957-1960 Box 3
 Brewer, George J.
1971 Box 3
 Brinkman, R.
1947-1948 Box 3
 Briscoe, Anne and William A.
1956-1971 Box 3
 British Drug Houses, Ltd
1932, 1952 Box 3
 British Embassy
1940-1941 Box 3
 British Empire Cancer Campaign
1956-1957 Box 3
 British Medical Bulletin
1961-1962 Box 3
 British Supply Council in North America
1941-1944 Box 3
 Brookhaven National Laboratory
1963 Box 3
 Brown, Bruce
1945 Box 3
 Brownrigg, P.H.A.
1957-1959 Box 3
 Bullard, Edward
1965 Box 3
 Bunn, Franklin H.
1970-1971 Box 3
 Burch, George
1948 Box 3
 Burns, W.
1956 Box 3
 Burton, Alan C.
1962 Box 3
 Butler, J.A.V.
1957-1961 Box 3
 Butterworths Scientific Publications
1948-1950 Box 3
 Buttery, H.A.
1957 Box 3
 C
1929-1971 Box 3
 Caldin, E.F.
1960-1963 Box 3
 Caldwell, Thomas B.
1971 Box 3
 Cambridge Instrument Company
1953-1959 Box 3
 Cannon, Walter B.
1923 Box 3
 Caplow, Michael
1968 Box 3
 Carpmaels & Ransford
1932-1933 Box 3

Patent agents

 Carroll, B.
1960 Box 3
 Carter, Martin J.
1970 Box 3
 Champerhoulie, David
1970 Box 3
 Chance, Britton
1940-1971, undated 4 folders Box 4
 Chatterji, A.C.
1960-1966 Box 4
 Chipperfield, J.R.
1961-1967 Box 4
 Clapp, Daniel B.
1948 Box 4
 Clark, A,M.
1949-1951 Box 4
 Clinical Chemistry
1963-1964 Box 4
 Cohn, E.J.
1947-1948 Box 4
 Collip, J.B.
1942 Box 4
 Common, R.H.
1940 Box 4
 Comroe, Julius H.
1947-1968 Box 4
 Connelly, ___
1941 Box 4
 Constantine, Herb
1962-1964 Box 4
 Corbellini, A.
1965-1966 Box 4
 Cort, J.H.
1954 Box 4
 Cotes, J.E.
1957-1959 Box 4
 Cottrell, A.H.
1958-1960 Box 4
 Courts, Albert
1967 Box 4
 Crank, J.
1959 Box 4
 Cunningham, D.J.C.
1960-1964 Box 4
 Czerlinski, Georg
1965 Box 4
 D
1932-1970 Box 4
 Dainton, F.S.
1957-1960 Box 4
 Dale, Henry H.
1931-1949 Box 4
 Daly, I. de Burgh
1946-1958 Box 4
 Daly, J.J.
1957-1962 Box 4
 Daly, M. de Burgh
1957 Box 4
 Dalziel, Keith
1952-1953 Box 4
 Danckwerts, P.V.
1961-1968 Box 4
 Danielli, J.F.
1960-1961 Box 4
 Daniels, H.E.
1951-1967 Box 4
 Darling, Robert C.
1945 Box 4
 Das, A.K.
1950-1971 Box 4
 Davenport, Horace W.
1938-1967 Box 5
 Davidson, J.F.
1966-1968 Box 5
 Davies, R.E.
1947-1962 Box 5
 Davis, R.P.
1958-1962 Box 5
 Dawson, Peter T.
1958-1959 Box 5
 Defandorf, James H.
1949 Box 5
 DeHaven, James
1962-1972 2 folders Box 5
 DeLand, Edward
1962-1971 2 folders Box 5
 Dennell, Ralph
1949 Box 5
 Dervichian, D.G.
1948 Box 5
 DeVoe, Howard
1959-1960 Box 5
 Dickens, F.
1946-1963 Box 5
 Dill, David Bruce
1940-1971 2 folders Box 5
 Dirken, M.N.J.
1948 Box 5
 Dodds, E.C.
1937-1938 Box 5
 Doerken, Peter
1965 Box 5
 Douglas, C.G.
1948-1962 Box 5
 Drabkin, David
1947-1949 Box 5
 DuBois, J.E.
1961 Box 5
 Dunn Laboratories
1956 Box 5
 DuPont Company
1956-1957 Box 5
 Duve, Christian de
1948 Box 5
 Dyson Perrins Laboratory
1961 Box 5
 E
1956-1966 Box 5
 Edsall, John T.
1947-1971 2 folders Box 5-6
 Edwards, Ethel
1946-1967, undated Box 6
 Eigen, M.
1958-1960 Box 6
 Eirich, Frederick R.
1949-1950 Box 6
 Eisler, Bedrich
1949 Box 6
 Eley, D.D.
1956-1961 Box 6
 Ellison, C.W.
1927-1928 Box 6
 Ernsting, J.
1965 Box 6
 European Office of Aerospace Research
1961-1966 Box 6
 Ewing, Ellen
1948-1958, undated Box 6
 Ewing, John
1953 Box 6
 Eyring, H.
1962-1963 Box 6
 F
1935-1965 Box 6
 Fatt, Irving
1961-1972 3 folders Box 6
 Faurholt, Carl
1956-1962 Box 6
 Fenn, Wallace O.
1943-1964 Box 6
 Ferguson, Kenneth
1934-1966 Box 6
 Fergusson, R.R.
1952-1956 Box 6
 Filley, Giles
1947-1966 Box 6
 Fink, Stanley
1969-1970 Box 6
 Fishman, A.P.
1965 Box 6
 Fitzwilliam, Earl
1964-1965 Box 6
 W.G. Flaig & Sons
1950-1963 Box 6
 Fletcher, C.M.
1945-1947 Box 7
 Folman, M.
1959 Box 7
 Forbes, William H.
1929-1971 2 folders Box 7

Other correspondents within the folders: Nan, David C., Pauline, T.R. and Anne.

 Forrest, W.W.
1948-1966 Box 7
 Forster, Robert E.
1951-1971 5 folders Box 7
 Fowler, Ward S.
1947 Box 7
 Fox, H. Munro
1948 Box 7
 Franklin, K.J.
1948-1950 Box 7
 Friess, S.L.
1957-1959 Box 7
 Fulton, John F.
1940-1949 Box 7
 G
1944-1971 Box 7
 Gaensler, Edward A.
1956 Box 7
 Garfinkel, David
1962-1968 Box 7
 George, Philip
1951-1956 Box 7
 Gettler, Joseph D.
1950 Box 7
 Gibson, Q.H.
1948-1972 12 folders Box 8-9
 Gilbert, G.A.
1964-1966 Box 9
 Gilding, H.P.
1959 Box 9
 Gillespie, F.S.
1943-1945 Box 9
 Glade, Rosa
1945 Box 9
 Glynn, L.E.
1947, 1967 Box 9
 Goldie, E.
1946 Box 9
 Goldstick, Thomas K.
1964-1965 Box 9
 Goodwin, T.W.
1965-1966 Box 9
 Gray, J.A.B.
1957-1963 Box 9
 Gray, L.H.
1956 Box 9
 Gregerson, Charlotte
1945-1971, undated Box 9
 Gregerson, Magnus I.
1943-1969 Box 9
 Gregor, Harry P.
1964-1965 Box 9
 Griesedieck Brothers Brewery Company
1955-1956 Box 9
 Griffiths, N.N.
1962 Box 9
 Arthur Guinness Son and Company
1959 Box 9
 Gutfreund, Herbert
1949-1971 Box 9
 H
1943-1972 Box 9
 Hahn, C.
1971-1972 Box 9
 Halperin, Meyer H.
1946-1958 Box 9
 Hambro, Carl
1956 Box 9
 Hammomd, A.
1960-1962 Box 9
 Hanai, T.
1962-1965 Box 9
 Hanania, G.
1950-1957 Box 9
 Harper, A.A.
1959-1960 Box 9
 Harper & Row Publishers
1963 Box 9
 Harris, Edward A.
1965-1966 Box 9
 Hartridge, Hamilton
1922-1972 Box 10
 Harvard University
1928-1945 Box 10
 Harwood, Mary
1964-1965 Box 10
 Hastewell, L.J.
1965-1966 Box 10
 Hatchett, S.P.
1958-1959 Box 10
 Haurowitz, Felix
1947-1970 Box 10
 Havelock, E.H.E.
1948 Box 10
 Haydon, D.A.
1958-1965 Box 10
 Helms, Hans Jorgen
1961-1965 Box 10
 Hemingway, Allan
1947-1970 Box 10
 Herzer, K.H.
1963-1966 Box 10
 Hewitt, Elaine
1946-1971 2 folders Box 10
 Hill, A.V.
1924-1970 Box 10
 Hill, Robert J.
1965-1966 Box 10
 Hodgkin, Alan
1958-1966 Box 10
 Hogan, Esther
1945-1949 Box 10
 Horvath, Steve & Betty
1943-1972 2 folders Box 10
 House renovations
1925-1927 Box 10
 Howe, V.A.
1957-1966 Box 10
 Hoyt, Anne
1945-1962 Box 10
 Hudson, S.G.
1957-1965 Box 10
 Huggett, A.
1948-1957 Box 10
 Hugh-Jones, P.
1959-1962 Box 10
 Huxley, Andrew
1940 Box 10
 Hvalradets Skrifter
1965 Box 10
 I
1951-1965 Box 11
 Imperial Chemical Industries
1932-1966 5 folders Box 11
 Ingram, V.M.
1959-1963 Box 11
 Interscience Publishers
1952-1962 Box 11
 J
1945-1961 Box 11
 Jackson, S.
1951 Box 11
 Janus, J.W.
1957 Box 11
 Jeffs, George M.
1964-1971 Box 11
 Jensen, Mogens B.
1962-1969 Box 11
 Joels, Norman
1957-1965 Box 11
 Johnson, Paley
1949-1971 Box 11
 Jonxis, J.H.P.
1948-1949 Box 11
 Jordan, R.C.
1957 Box 11
 Journal of Biological Chemistry
1941-1967 Box 11
 Journal of Clinical Investigation
1962-1966 Box 11
 Journal of Molecular Biology
1966-1971 Box 11
 Journal of Physical Chemistry
1962-1963 Box 11
 Journal of Physiology
1956-1966 Box 11
 Journal of Theoretical Biology
1967 Box 11
 K
1924-1966 Box 11
 Karvonen, M.J.
1948-1955 Box 11
 Keilin, D.
1948-1951 Box 11
 Kelman, G.R.
1966-1968 Box 11
 Kendrew, J.C.
1948-1966 Box 11
 Kernohan, John C.
1956-1971 2 folders Box 12
 Kiese, Manfred
1952-1953 Box 12
 King, Daphne
1944-1966 Box 12
 Kipping, F.B.
1957-1964 Box 12
 Kirschbaum, T.H.
1962-1966 Box 12
 Kistiakowaky, G.B.
1958 Box 12
 Klug, Aaron
1953-1961 Box 12
 Knowles, G.
1959-1963 Box 12
 Kratochvil, C.H.
1961-1963 Box 12
 Krebs, H.A.
1946-1971 Box 12
 Kreuzer, Ferdinand
1950-1972 4 folders Box 12
 Krogh, A.
1946-1949 Box 12
 L
1932-1972 Box 12
 Laboratory equipment
1947-1964 Box 12
 Ladell, W.S.S.
1958-1960 Box 12
 LaForce, R.C.
1962-1963 Box 12
 Lamb, Alice
1945-1948 Box 12
 Lamb & Holmes
1926-1967 Box 12
 Lamb, Winifred
1956-1967, undated Box 13

Cousin.

 Lawrence, John H.
1944-1962 Box 13
 Lecture series
1940-1941 Box 13

Lectures given at Universities in the United States.

 Lederle Laboratories
1956-1958 Box 13
 Leeuwen, A.M.
1956-1962 Box 13
 Legge, J.W.
1950-1957 Box 13
 Lenfant, Claude
1971 Box 13
 Libby, W.F.
1964-1966 Box 13
 Life magazine
1950 Box 13
 Lilienthal, J.L.
1944-1950 Box 13
 Lindsey, D.C.
1962 Box 13
 Lipmann, Fritz
1957 Box 13
 Litchfield, J.T.
1954-1956 Box 13
 Livingston Laboratories
1965 Box 13
 Lloyd, B.B.
1961-1963 Box 13
 Long, Perrin H.
1942 Box 13
 Longmans Green and Company
1947-1949 Box 13
 Longmuir, I.S.
1948-1965 Box 13
 Lovett, S.J.
1963 Box 13
 Lullies, H.
1959-1960 Box 13
 Lumry, Rufus
1957-1968 Box 13
 Lund, Vibeke
1951 Box 13
 Lyster, R.L.J.
1949-1968 Box 13
 M
1924-1972 Box 13
 MacArthur, William
1961-1962 Box 13
 MacFarlane, M.
1949 Box 13
 MacFarlane, R.G.
1958-1959 Box 13
 MacPherson, R.E.
1948 Box 13
 Madge, Edith
1922-1932, undated Box 13
 Manchester College of Science and Technology
1958 Box 13
 Mann, F.G.
1947 Box 13
 Mapleson, W.W.
1963 Box 13
 Margaria, R.
1948 Box 13
 Maren, Thomas
1962-1972 Box 13
 _______, Marjorie
1964-1971 Box 13
 Markham, E.
1964 Box 13
 Mathai, K.G.
1954-1963 Box 13
 Matthews, Bryan
1940-1964 Box 13
 Maxwell, Magdalene (Mrs. Perceval)
1964-1966 Box 13
 McCarthy, E.F.
1948 Box 14
 McFarland, Ross A.
1947-1972 Box 14
 McLellan, B.G.
1956-1960 Box 14
 McPhail, M.K.
1945 Box 14
 Meade, F.
1959-1967 Box 14
 Meda, Eugenio
1951-1972 Box 14
 Meldrum, Elizabeth
1948 Box 14
 Mellanby, Edward
1940 Box 14
 Merriman, Daniel
1949-1957 Box 14
 Millikan, Glenn
1929-1946 4 folders Box 14
 Mills, G.A.
1942 Box 14
 Miner, Eunice
1957-1966 Box 14
 Ministry of Labour and National Service
1943-1945 Box 14
 Ministry of Munitions of War
1917-1918 Box 14
 Ministry of Production
1943-1945 Box 14
 Ministry of Supply
1939-1949 Box 14
 Minkowski, Alexandre
1959 Box 14
 Miscellaneous
1923-1967 Box 14
 Mitchell, J.S.
1948-1950 Box 14
 Mochizuki, Masaji
1956-1963 Box 14
 _______, Molly
1947-1950 Box 14

Sister-in-law

 Monro, P.
1964 Box 14
 Moore, A.D.
1945 Box 14
 Moore, Walter J.
1962-1963 Box 14
 Mott, N.F.
1957-1965 Box 14
 Myrback, Karl
1940-1949 Box 14
 N
1940-1966 Box 14
 Nastuk, William L.
1948-1969 Box 14
 Nature
1946-1970 Box 14

Periodical

 Neil, E.
1956-1964 Box 14
 Neuberger, A.
1949-1968 Box 14
 Neuda, Paul M.
1948 Box 14
 Neurath, Hans
1953 Box 14
 Neville, J.Ryan
1961 Box 15
 Newkirk, Janet
1964-1966 Box 15
 New Scientist
1957 Box 15
 Nickerson, John L.
1942-1958 Box 15
 Nicolson, Phyllis
1946-1951 Box 15
 Noble, Robert
1944 Box 15
 O
1943-1964 Box 15
 O'Brien, J.R.P.
1948-1970 Box 15
 Ogilvie, C.M.
1956 Box 15
 Oldham, F.
1955 Box 15
 Organic Chemical Corporation
1956 Box 15
 O'Rourke, L.
1957-1960 Box 15
 Otis, Arthur B.
1948-1971 2 folders Box 15
 Ottewill, R.H.
1952-1965 Box 15
 P
1948-1970 Box 15
 Paganelli, C.V.
1958 Box 15
 Pappenheimer, John Richard
1950 Box 15
 Paul, William
1947-1966 Box 15
 Pauling, Linus
1944-1960 Box 15
 Pearson, L.
1956-1958 Box 15
 Pedersen, Kai O.
1948 Box 15
 Pennell, Robert B.
1947 Box 15
 Pergamon Press
1958-1963 Box 15
 Perrin, Douglas D.
1947-1963 Box 15
 Perutz, Max F.
1960-1966 Box 15
 Peters, R.A.
1948 Box 15
 Pethica, B.A.
1956-1964 Box 15
 Petroleum Warfare Department
1943-1946 Box 15
 Phillips, C.G.
1961-1966 Box 15
 Piggins, K.A.
1961-1963 Box 15
 Pinsent, Brian R.W.
1948-1965 Box 15
 Pochin, Bill
1944 Box 15
 Pomerat, Gerard R.
1952-1957 Box 15
 Popjak, G.
1948 Box 15
 Prince, R.H.
1956-1960 Box 15
 Pugh, L.G.
1965 Box 15
 Proskauer, E.S.
1956-1963 Box 15
 Pyle, C.
1955-1956 Box 15
 Quastel, J.H.
1953-1960 Box 15
 Quagliariello, G.
1954 Box 15
 R
1927-1972 Box 15
 Rahn, Hermann
1963 Box 15
 Rahr Malting Company
1956 Box 15
 Ramsay, W.N.M.
1948-1949 Box 16
 Rand Corporation
1963-1967 2 folders Box 16
 Randall, J.W.
1961-1966 Box 16
 Redfield, Alfred C.
1964-1966 Box 16
 Redman, Harold
1965-1966 Box 16
 Relman, Arnold S.
1953-1966 Box 16
 Research: a Journal of Science
1949-1950 Box 16
 Richards, Dickinson W.
1962 Box 16
 Rideal, E.K.
1957-1960 Box 16
 Riggs, Austen
1959-1971 Box 16
 Rimington, C.
1948-1950 Box 16
 Robertson, Ainslie J.
1946-1965, undated Box 16
 Robertson, Phyllis
1945-1964 Box 16
 Robinson, Sid
1944-1961 Box 16
 Robinson, T.S.
1948-1950 Box 16
 Roche, Jean
1947-1948 Box 16
 Rockefeller Institute Press
1964-1965 Box 16
 Root, Walter
1943-1966 Box 16
 Rossi-Fanelli, A.
1948-1954 Box 16
 Rossi, Luigi
1961-1972 6 folders Box 16-17

Also known as: Luigi Rossi-Bernardi.

 Roughton, Alice
1924-1972, undated 5 folders Box 17

Wife

 Roughton, Audrey and Peter
1946-1970 Box 17

Cousin.

 Roughton, Dorothy W.
1912-1930 Box 17

Sister

 Roughton, G.W.
1862 Box 17
 Roughton, Geoffrey
1945-1972, undated Box 17

Son

 Roughton, Hugh
1933 Box 17
 Roughton, J.P.
1918-1937, undated Box 17

Father

 Roughton, Mrs. J.P.
1908-1931, undated 6 folders Box 17-18

Mother

 Roughton, Janet
1951 Box 18
 Roughton, Roger
1946-1967, undated 4 folders Box 18-19
 Roughton, Rosemary
1938-1966 Box 19

Daughter

 Roughton, S.J.W.
1957 Box 19
 Roughton, Winifred and Nora
1938-1967 Box 19
 Rowe, A.J.
1958-1961 Box 19
 Rupp, Joseph
1955-1960 Box 19
 S
1944-1972 Box 19
 Saint Helen, Roger
1969 Box 19
 Sandroy, Julius
1948 Box 19
 Scantlebury, Ronald E.
1957-1959 Box 19
 Scholander, Per Fredrik
1942-1965 Box 19
 School of Aerospace Medicine
1961 Box 19
 Schulman, J.H.
1949-1958 Box 19
 Schuster, Todd
1965-1966 Box 19
 Science Progress
1958-1962 Box 19
 Scorah, R.
1966 Box 19
 Scott, D.A.
1949 Box 19
 Seaton, Brian
1970-1972 Box 19
 Semple, S.J.G.
1962-1967 Box 19
 Sendroy, Julius
1945-1971 Box 19
 Severinghaus, John W.
1957-1967 Box 19
 Shargel, Richard
1970-1971 Box 19
 Sherwood-Jones, E.
1949-1958 Box 19
 Sirs, John A.
1951-1964 2 folders Box 19
 Slater & Dominy
1944-1945 Box 19
 Sluyterman, L.
1960-1961 Box 19
 Smith, Emil
1953-1963 Box 19
 Smith, Malcolm Herbert
1958-1969 Box 19
 Solandt, O.M.
1942-1943 Box 20
 Sollner, Karl
1958 Box 20
 _____, Sophie
1958 Box 20
 Stainsby, G.
1958-1959 Box 20
 Stannard, J.N.
1944-1945 Box 20
 Staub, N.C.
1959-1962 Box 20
 Stein, W.D.
1959-1962 Box 20
 Stevens, Charles D.
1942-1944 Box 20
 Stratmann, C.J.
1950-1951 Box 20
 Strehler, Allen F.
1953-1954 Box 20
 Sturtevant, Julian M.
1953-1958 Box 20
 Sumner, James B.
1949 Box 20
 Sundnes, Gunnar
1964-1965 Box 20
 Sutherland, G.B.B.M.
1948-1953 Box 20
 T
1949-1967 Box 20
 Thews, G.
1957-1959 Box 20
 Thoday, J.M.
1965-1966 Box 20
 Thomson, L.C.
1953-1963 Box 20
 Thorne, P.A.C.
1957-1958 Box 20
 Tilley, C.E.
1948-1960 Box 20
 Tompkins, ___
Undated Box 20
 Trotman-Dickenson, A.F.
1948 Box 20
 Trurnit, H.
1954 Box 20
 Twining, Georgina
1964 Box 20
 U
1960-1963 Box 20
 Underwood, A.L.
1960 Box 20
 University Laboratory of Physiology-Oxford
1960-1963 Box 20

J.S. Haldane Centenary Symposium.

 University of Birmingham
1954 Box 20
 University of Dundee
1968 Box 20
 University of Leeds
1966 Box 20
 University of London
1932-1964 Box 20
 University of Pennsylvania
1950 Box 20
 University of Sheffield
1958 Box 20
 V
1947-1965 Box 20
 Van Leeuwen, A.M.
1956-1962 Box 20
 Vannotti, A.
1948 Box 20
 Van Slyke, Donald D.
1932-1970 Box 20
 Vidal-Hall, A.
1948 Box 20
 Vincent House
1952-1967 Box 20
 Visser, B.F.
1963 Box 20
 W
1929-1966 Box 20
 Wald, George
1953-1956 Box 20
 Waldam, Simon P.
1969 Box 20
 Wallach, Donald F.H.
1964 Box 20
 War Office
1915-1950 Box 20
 Ward, A.G.
1956-1961 Box 21
 Warner, W.J.N.
1957-1966 Box 21
 Weber, Hans H.
1959-1964 Box 21
 Weiler, Madame
1956 Box 21
 Weissberger, A.
1953-1960 Box 21
 West, John B.
1957-1960 Box 21
 Wharton, David C.
1966-1967 Box 21
 White, H.L.
1953 Box 21
 White, L.P.
1957-1958 Box 21
 Whittingham, H.E.
1940-1941 Box 21
 Wiggers, Carl J.
1943-1944 Box 21
 John Wiley and Sons, Inc.
1962-1966 Box 21
 Wilkins, D.J.
1957-1961 Box 21
 Wolvekamp, H.P.
1948-1949 Box 21
 Woolley, Russell
1937-1965 Box 21
 Worchester, Elizabeth
1949 Box 21
 Worthington Biochemical Corporation
1955-1956 Box 21
 Wright, Samson
1949 Box 21
 Wyman, Jeffries
1947-1972 2 folders Box 21
 Y
1958-1964 Box 21
 Young, I.M.
1948-1950 Box 21
 Z
1959-1966 Box 21
 Zambotti, V.
1963-1965 Box 21
 Zvegintzov, M.
1953-1959 Box 21
 Series II. Organizations, Foundations and Conferences
1923-1972 Box 22-30
 Aero Medical Association
1940-1942 Box 22
 Agricultural Research Council
1957-1968 Box 22
 Alfred Benzon Foundation
1970-1971 Box 22
 American Academy of Arts and Sciences
1970-1971 Box 22
 American Institute of Biological Sciences
Undated Box 22
 American Physiological Society
1957-1965 2 folders Box 22