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MANUSCRIPT COLLECTION

Dates:
1929-1992
Abstract:  

A biochemist at Columbia University, Erwin Chargaff discovered the base-pairing regularities or "complementarity relationships" of nucleic acids that provided one of the key steps in developing a structural model for DNA. During his long career, Chargaff is credited with conclusively falsifying the tetranucleotide hypothesis; demonstrating the existence of a large number of DNA species; and creating the first descriptions of hypochromicity, hyperchromicity, and the denaturation of a DNA. In addition, Chargaff conducted important research on blood coagulation, lipids and lipoproteins, the metabolism of amino acids and inositol, and the biosynthesis of phosphotransferases. He retired to emeritus status in 1974 and remained active in research almost to the time of his death in June 2002. The Chargaff Papers are organized into ten series: I. Correspondence, 1931-1992; Ia. Correspondence, 1949-2002; IIa. Grants, 1930-1982; IIb. Subject Files, 1940-1984; IIc. Subject Files, 1946-2002; III. Works by Chargaff, 1929-1989; IIIa. Works by Chargaff, 1923-2002; IIIb. Reprints, 1977-1999; IV. Works by Others, 1936-1985; IVa. Works by Others, 1976-2002; V. Research Notes and Notebooks, 1929-1951 ; VI. Photographs, 1935-1977; VIa. Photographs, 1928-2002; VII. Audiovisual Materials; VIII. Awards and Certificates, 1958-2001; IX. Lecture Notes, 1942-1985; X. Personal Papers, [1880]-1985.
Call #:  
Mss.B.C37
Extent:
56 Linear feet
Subjects:  

American Association for the Advancement of Science | American Cancer Society | American Chemical Society | American Institute of Biological Sciences | Anderson, Rudolph J. (Rudolph John), 1879-1961 | Astbury, William Thomas | Atomic Energy Commission | Bacterial genetics | Barzun, Jacques, 1907-2012 | Bibliographical matters | Biochemistry and organic chemistry | Biochemistry and organic chemistry -- Nomenclature | Biochemistry. | Biochimica et Biophysica Acta | Biographical and personal data -- Haldane, John Burdon Sanderson | Brawerman, George | Burris, Robert H. (Robert Harz | Business | Cancer, chemotherapy | Carter, Herbert E. | Chargaff, Erwin | Chargaff, Erwin, 1905-2002 | Columbia University | Columbia University. | Committee activities | Conferences and symposia | Conferences and symposia -- Gordon Conferences | Congratulations, greetings, thanks | Congratulations, greetings, thanks -- National Academy of Sciences | Congratulations, greetings, thanks -- Nobel Prize | Crick, Francis H. C. | Crick, Francis, 1916-2004 | Cytogenetics | DNA | Davidson, J. N. (James Norman) | Doty, Paul | Editorial matters | Editorial matters -- Biochimica et Biophysica Acta | Edsall, John T. (John Tileston), 1902-2002 | Educational matters | Ephrussi, Boris | Ethical issues | Gamow, George, 1904-1968 | Genetics | Genetics of plants | Gusarev, V. | Hardin, Garrett James, 1915-2003 | History of biology, especially genetics | Hollaender, Alexander | Honors | Honors -- National Academy of Sciences | Honors -- Nobel Prize | Human genetics | Inositol | Kusch, Polykarp, 1911-1993 | Laboratory notebooks | Laboratory techniques, equipment | Lectures, public speaking | Lederberg, Joshua | Lederer, Edgar. | Lipoproteins | McClintock, Barbara, 1902-1992 | Medical research | Molecular genetics | National Academy of Sciences | National Academy of Sciences (U.S.) | National Academy of Sciences -- Meeting minutes | National Academy of Sciences -- Reports | Nucleic acids | Nucleic acids -- Structure | Oak Ridge National Laboratory | Pauling, Linus | Pauling, Linus, 1901-1994 | Perutz, Max F. | Phosphotransferases | Photoprints | Political issues | Protozoan genetics | Publication | Publication -- Biochimica et Biophysica Acta | Publication -- New Scientist | Publication -- Pravda | Publication -- The Eighth Day of Creation | RNA tie club | Recombinant DNA | Requests for aid in finding positions | Requests for reprints | Reviews | Reviews -- Amphisbaena | Reviews -- Heraclitean Fire | Runnstrom, John. | Russian politics and science | Russian politics and science -- Lysenko, Trofim Denisovich | Schmitt, Francis Ottom, 1903- | Stanacev, Nikola Z. | Stent, Gunther S. | Stern, Curt | Straus, Werner | Travel -- Invitations, arrangements | Travel -- U.S.S.R. | United States. Office of Scientific Research and Development | United States. Public Health Service | Unpublished manuscripts, notes, etc. | Waelsch, Heinrich B. | Watson, James D. | Watson, James D., 1928- | World War II -- Impact on science



BOOK

Title:  
Heraclitean fire: sketches from a life before nature
Creator:
Chargaff, Erwin.
Publication:
Rockefeller University Press, New York, 1978.
Notes:  
Includes index. Bibliography: p. 229-252.
Call #:  
B C37h
Extent:
[ii] 252 p. ; 23 cm.



ANALYTIC

Title:  
Erwin Chargaff: 11 August 1905-20 June 2002
Parent:
American Philosophical Society. Proceedings, v.148, no.2
Creator:
[Cohen, Seymour S. (Seymour Stanley)], 1917-
Publication:
Philadelphia, Pa, 2004.
Call #:  
506.73 AM4P V.148, NO.2
Extent:
p. [221]-228. : port. ; 26 cm.



ANALYTIC

Title:  
From biochemistry to molecular biology: DNA and the acculturated journey of the critic of science Erwin Chargaff
Parent:
History and philosophy of the life sciences, v.2, no.1
Creator:
Abir-Am, Pnina G., 1947-
Publication:
Firenze, 1980.
Call #:  
506.45 N16p v.2, no.1
Extent:
p.3-60 p. ; 24 cm.



BOOK

Title:  
Kritik der Zukunft
Creator:
Chargaff, Erwin.
Publication:
Klett-Cotta, Stuttgart, c1983.
Notes:  
Includes bibliographical references.
Call #:  
501.4 C37K
Extent:
142 p. ; 18 cm.



BOOK

Title:  
Zeugenschaft: Essays über Sprache und Wissenschaft
Creator:
Chargaff, Erwin.
Publication:
Klett-Cotta, Stuttgart, c1985.
Notes:  
Includes bibliographical references and index.
Call #:  
501.4 C37Z
Extent:
239 p. ; 22 cm.



BOOK

Title:  
Warnungstafeln: die Vergangenheit spricht zur Gegenwart
Creator:
Chargaff, Erwin.
Publication:
Klett-Cotta, Stuttgart, c1982.
Notes:  
Includes bibliographical references and index.
Call #:  
501.4 C37W
Extent:
266 p. ; 22 cm.



BOOK

Title:  
Serious questions: an ABC of skeptical reflections
Creator:
Chargaff, Erwin.
Publication:
Birkhäuser, Boston, [1986]
Notes:  
"A Pro scientia viva title." Includes bibliographical references.
Call #:  
B C37S
Extent:
viii, 261 p. ; 22 cm.



BOOK

Title:  
Evolution: Vortrage anlässlich der Jahresversammlung vom 11. bis 14. Oktober 1973 zu Halle (Saale)
Creators:
Deutsche Akademie der Naturforscher Leopoldina | Scharf, Joachim-Hermann | Kaiserlich Leopoldinisch-Carolinische Deutsche Akademie der Naturforscher
Publication:
Deutsche Akademie d. Naturforscher Leopoldina, Barth, Halle (Saale), Leipzig, 1975.
Notes:  
Accompanied by 2 records. Includes bibliographies.
Call #:  
506.43 K12A BD.42
Extent:
668 p. : ports., illus., maps, fold. tables, diagrs. ; 24 1/2 cm.



BOOK

Title:  
The nucleic acids: Chemistry and biology
Creators:
Davidson, J. N. (James Norman) | Chargaff, Erwin.
Publication:
Academic Press, New York, 1955.
Notes:  
Includes bibliographical references and indexes.
Call #:  
574.19 N89C
Extent:
v. ill., charts, tables ; 24 cm.



BOOK

Title:  
[Miscellaneous reprints. 2 sets]
Creator:
Chargaff, Erwin.
Publication:
1928-1976.
Notes:  
Various places.
Call #:  
574.19 PAM.C
Extent:
6 boxes. various sizes.



BOOK

Title:  
Essays on nucleic acids
Creator:
Chargaff, Erwin.
Publication:
Elsevier Pub. Co, Amsterdam, New York, 1963.
Notes:  
Includes bibliography.
Call #:  
574.19 C37E
Extent:
211 p. illus. 22 cm.



MANUSCRIPT COLLECTION

Dates:
1938-1990
Abstract:  

Working on bacterial viruses in 1945, Seymour S. Cohen offered the first systematic exploration of the biochemistry of virus-infected cells and of how viruses multiply. His subsequent research included delineating the phenomenon of thymineless death, developing derivatives of ara-A compound, working on RNA synthesis, studying the effects of polyamines on metabolic systems, and studying plant viruses (including viral cations). Much of his research has contributed to the chemical treatment of cancer and viral infections.
Call #:  
Mss.Ms.Coll.48
Extent:
26 Linear feet
Subjects:  

American Association for Cancer Research | American Cancer Society | Avery, Oswald Theodore | Bachrach, Uriel, 1926- | Bacterial genetics. | Bacteriophage and viral genetics | Behrens, Otto Karl, 1911-1989 | Beljanski, Mirko, 1923-1998 | Bendich, Aaron, 1917-1979 | Benzer, Seymour, 1921-2007 | Berg, Paul, 1926- | Biochemistry and organic chemistry | Biographical and personal data | Borek, Ernest, 1911-1986 | Brachet, J. (Jean), 1909-1988 | Bukantz, Samuel C | Cancer -- Research | Cancer, chemotherapy | Chargaff, Erwin, 1905-2002 | Children's Hospital of Philadelphia | Cohen, Seymour S. (Seymour Stanley) | Cold Spring Harbor Laboratory | Commonwealth Fund. | Conferences and symposia | Conferences and symposia -- Chargaff, Erwin | Congratulations, greetings, thanks -- Charles-Leopold Mayer Prize | Congratulations, greetings, thanks -- National Academy of Sciences | Davis, Bernard D., 1916-1994 | Delbrück, Max, 1906-1981 | Ethical issues | Fox, Jack Jay, 1916- | Fruton, Joseph S. (Joseph Stewart) | Genetics Society of America -- Golden Jubilee | Goldfarb, David | Hershey, A. D. (Alfred Day) | History of biology, especially genetics | Hollaender, Alexander | Honors -- National Medal of Science | Honors -- Nobel Prize | Horecker, Bernard L. (Bernard Leonard), 1914- | Indiana University | Invitations | Kabat, Elvin A. (Elvin Abraham), 1914- | Kanazir, Dus̆an | Khouvine, Yvonne | Kornberg, Arthur, 1918- | Laboratory notebooks | Laboratory notes | Laboratory techniques, equipment | Lauffer, Max A. (Max Augustus), 1914- | Lectures, public speaking | Lederberg, Joshua | Luria, S. E. (Salvador Edward), 1912-1991 | Luria, Salvador Edward | Macura, Anna B | Molecular genetics | Monod, Jacques, 1910-1976 | Nucleic acids | Oak Ridge National Laboratory | Olby, Robert Cecil | Pauling, Linus, 1901-1994 | Polyamines | Protozoan genetics | Publication | Radiation genetics | Recommendations | Requests for reprints | Schabel, Frank Milton, Jr. 1918-1983 | Scientific organizations, meetings, programs | Sonneborn, T. M. (Tracy Morton), 1905-1981 | Spiegelman, Solomon, 1914- | Stanley, Wendell M. (Wendell Meredith), 1904-1971 | Travel -- Invitations, arrangements | University of Pennsylvania. | Unpublished manuscripts, notes, etc. | Upjohn Company. | Viral genetics | Weed, Lawrence L | Weigle, Jean | Wyatt, Gerard Robert, 1925-



MANUSCRIPT COLLECTION

Dates:
1968-1978
Abstract:  

Between 1968 and 1978, the historian of science Horace Freeland Judson conducted extensive oral history interviews with biochemists and molecular biologists relating to the development of their field. The correspondence, transcripts of interviews, and taped interviews that comprise the Judson collection formed the research material used by Judson in his book, The Eighth Day of Creation (New York, 1979). Permission to quote must be obtained from Dr. Judson and access to some files is restricted.
Call #:  
Mss.B.J92
Extent:
1 Linear feet
Subjects:  

Ames, Bruce N., 1928- | Audureau, Alice | Bacterial genetics | Bacteriophage and viral genetics | Baltimore, David | Barnett, Leslie, 1920-2002 | Beadle, George Wells | Beckett, Samuel, 1906-1989 | Behavioral genetics, IQ | Benzer, Seymour, 1921-2007 | Berg, Paul, 1926- | Biochemistry and organic chemistry | Biographical and personal data | Blow, David | Bodmer, W. F. (Walter Fred), 1936- | Bohr, Niels | Bragg, William Lawrence, Sir, 1890-1971 | Brenner, Sydney, 1927-2019 | Bridges, Calvin B. | Brown, Angela Martin | Cairns, John | California Institute of Technology | Cambridge University | Cancer, chemotherapy | Caspersson, Torbjörn (Torbjörn Oskar), 1910-1997 | Cavendish Laboratory (Cambridge, England) | Chargaff, Erwin | Chargaff, Erwin, 1905-2002 | Cohen, Georges | Cohn, Melvin | Cold Spring Harbor Laboratory | Cowan, Pauline | Crick, Francis H. C. | Crick, Francis, 1916-2004 | Crick, Francis--with Maddox, John | Crick, Francis--with Olby, Robert | Crick, Odile | Cytogenetics | DNA -- History | Davern, Cedric | Delbruck, Max | Delbrück, Max, 1906-1981 | Donohue, Jerry | Drosophila genetics | Dubos, René | Dulbecco, Renato | Dunitz, Jack D. | Educational matters | Embryology, developmental genetics | Engelhardt, Vladimir Alexandrovich | Ephrussi, Boris, 1901-1979 | Ethical issues | Eugenics | Evolution | Fell, Dame Honor | Fourcade, Bertrand | Fraenkel-Conrat, Heinz | Fraser, Mary J. | Furberg, Sven | Gamow, George | Garen, Alan | Gilbert, Walter | Gosling, Ray | Griffiths, Wendell--with Olby, Robert | Gros, François | Grunberg-Manago, Marianne | Guidotti, Guido | Guillemin, Roger | Gurdon, John | Harrison, Pauline Cowan | Haurowitz, Felix | Hayes, William | Heppel, Leon | Hershey, A. D. (Alfred Day) | History of biology, especially genetics | Hoagland, Mahlon | Hodgkin, Dorothy Crowfoot | Hogness, David | Holley, Robert W. | Honors -- Nobel Prize | Horecker, Bernard | Hotchkiss, Rollin Douglas, 1911-2004 | Hubel, David | Hussain, Farooq | Huxley, Hugh | Ingram, Vernon M. | Institut Pasteur (Paris, France) | Jackson, Sylvia Fitton | Jacob, Francois, 1920-2013 | Judson, Horace Freeland, 1931-2011 | Jungelson, Eugene | Kalckar, Herman M. (Herman Moritz), 1908-1991 | Kendrew, John | Keynes, Richard D. | Kierkegaard quotation | Klug, Aaron | Kornberg, Roger | Lectures, public speaking | Lederberg, Joshua | Lennox, E. S. (Edwin Samuel) | Lerman, Leonard | Lewis, Herman | Lipmann, Fritz | Lipscomb, William N., 1919-2011 | Luria, S. E. (Salvador Edward), 1912-1991 | Luzzati, Vittorio | Lwoff, André | M'Ewen, Marjorie | Maaløe, Ole | Maas, Werner | Maddox, John | Markham, Roy | Matthaei, Heinrich | McClintock, Barbara, 1902-1992 | Medawar, P. B. (Peter Brian), 1915-1987 | Medvedev, Zhores A., 1925-2018 | Mertz, Janet | Meselson, Matthew | Miller, Stanley | Mitchison, Avrian | Molecular biology -- History | Molecular genetics | Monod, Jacques | Monod, Jacques | Monod, Olivier | Monod, Phillipe | Morgan, Thomas Hunt | Mouse genetics | National Institutes of Health | Nirenberg, Marshall W., 1927-2010 | North, Margaret Pratt | Noufflard, Geneviève | Ochoa, Severo | Olby, Robert | Oral histories | Orgel, Leslie | Pardee, Arthur | Pauling, Linus | Pauling, Linus, 1901-1994 | Pauling, Peter | Perrin, David | Perutz, Max | Phillips, David | Philosophy of science | Political issues | Pollack, Robert | Population, demography | Potter, Lincoln | Protozoan genetics | Ptashne, Mark | Publication -- The Double Helix | Publication -- The Eighth Day of Creation | Research support | Rich, Alexander | Ruderman, Warren | Russian politics and science | Russian politics and science -- Lysenko, Trofim Denisovich | Sanger, Frederick | Sayre, Anne | Schachman, Howard | Schmidt, Benno | Schultz, Jack | Shils, E.A. | Singer, Maxine | Smith, John | Spear, Walter Eric | Stent, Gunther | Stoker, Michael | Stokes, Alexander | Sturtevant, Alfred Henry | Swift, Hewson | Szent-Gyorgi, Andrew Gabriel | Temins, Howard | Terheggen, Heinz Georg | Thomas, Charles | Tissières, Alfred | Travers, Andrew | Ullman, Agnès | University of Chicago | Unpublished manuscripts, notes, etc. | Watson, James D. | Watson, James D. | Weil, Adrienne | Wilkins, Maurice | Wollman, Élie | World War II -- France | Wyatt, Gerard | Yanofsky, Charles | Zamecnik, Paul | Zea (maize) genetics



MANUSCRIPT COLLECTION

Dates:
Circa 1903-1973
Abstract:  

This collection contains correspondence, reports, notes, and notebooks. Clarke's participation in various organizations is documented, including the American Philosophical Society, American Chemical Society, American Otological Society, and the American Society of Biological Chemists. His chemistry research is detailed in thirteen notebooks, 1903-1971 (the 1903 volume is on photographic chemistry and processes). There is also one volume on the clarinet, for Clarke was an expert clarinetist. The personal and family correspondence is principally with Mrs. Dorothy Clarke Middleton and Mrs. Agnes Helfreich Clarke.
Call #:  
Mss.B.C55
Extent:
3 Linear feet



MANUSCRIPT COLLECTION

Dates:
1930-1945
Abstract:  

Papers consist of letters, reports, addresses and lectures, relating to biological chemistry and other scientific topics, the Rockefeller Institute for Medical Research, refugee scientists, professional associations, etc.
Call #:  
Mss.B.B445
Extent:
7.5 Linear feet



MANUSCRIPT COLLECTION

Dates:
1898-1956
Abstract:  

A pioneer biochemist, Carl Neuberg (1877-1956) spent over thirty years of his productive career as a professor at the University of Berlin (1903-1937) and as Director of the Kaiser Wilhelm Institutes of Biochemistry and Experimental Therapy. His varied research interests resulted in important contributions to the understanding of fermentation processes, solubility and transport phenomena in cells, the chemistry of carbohydrates, sugars, enzymes, and amino acids, and photochemistry. Neuberg was forced out of his position after the Nazi rise to power, and taking refuge in the United States. For the last several years of his life, he worked at New York University. The Neuberg collection consists of correspondence, lab notebooks, documents, photographs, and reprints, nearly all dating from after Neuberg's departure from Germany in 1940. The correspondence documents Neuberg's late-career work and the contacts he developed with American chemical manufacturers and industries involved in fermentation, as well as the burgeoning post-war relationship between scientific research and the federal dollar. Files for the American Cancer Society, U.S. Atomic Energy Commission, and the U.S. Public Health Service in particular contain useful information for study of the politics and mechanics of government grants.
Call #:  
Mss.Ms.Coll.4
Extent:
13.5 Linear feet



MANUSCRIPT COLLECTION

Dates:
1906-1970
Abstract:  

For his pioneering research on the link between viruses and cancer, the pathologist Francis Peyton Rous was awarded the Nobel Prize in Medicine in 1966. Working primarily at the Rockefeller Institute after 1909, Rous first came to notice for his theoretical construction of the first blood bank for use in France during World War I, a plan ultimately implemented by his assistant, Oswald H. Robertson. Subsequently, he left an important imprint on the development of experimental medicine, partly through his own research on the origins of cancer and his administrative activities at the Rockefeller, but also as editor of the Journal of Experimental Medicine from 1921-1970. The Rous Papers include correspondence, lectures, articles, reports, laboratory records, reprints, and photographs that document all aspects of the life and work of Peyton Rous. Reflecting his work at the Institute are letters of colleagues, information on assistants, and reports to the directors (1909-1959). Additional material relates to Rous' diverse organizational interests, including the American Cancer Society, Century Association, Jane Coffin Childs Memorial Fund for Medical Research (at Yale University), Federation of American Societies for Experimental Biology, Johns Hopkins University, National Academy of Sciences, National Research Council, New York Academy of Medicine, Royal Society of Medicine Foundation, and Sloan-Kettering Institute for Cancer Research.
Call #:  
Mss.B.R77
Extent:
71.5 Linear feet
Subjects:  

Addis, Thomas, 1881-1949 | American Cancer Society | Andrewes, C. H. (Christopher Howard), 1896-1988 | Articles | Baudisch, Oskar, 1881-1950 | Bayne-Jones, Stanhope, 1888-1970 | Beard, Joseph W. (Joseph Willis), 1901-1983 | Berenblum, I. (Isaac), 1903-2000 | Blankenhorn, Marion A. (Marion Arthur), 1885-1957 | Blood -- Research | Blood banks | Bronk, Detlev W. (Detlev Wulf), 1897-1975 | Cancer -- Research | Cattell, James McKeen, 1860-1944 | Century Association (New York, N.Y.) | Compton, Arthur Holly, 1892-1962 | Corner, George Washington, 1889-1981 | Crutcher, Katherine G. | Cutler, Richard B. | DeMaeyer, E. M. | Dean, Henry R. | Dolman, Claude E. (Claude Ernest), 1906-1994 | Dubos, René J. (René Jules), 1 | Federation of American Societies for Experimental Biology. | Flexner, Simon, 1863-1946 | Gasser, Herbert Spencer, 1888- | Gilding, Henry P. | Gregg, Alan, 1890-1957 | Gye, Will E. | Hevesy, Georg von, 1885-1966 | Huggins, Charles Brenton, 1901-1997 | Johnson, Earl | Journal of Experimental Medicine | Karsner, Howard Thomas, b. 187 | Kidd, John Graydon, 1908- | Krumbhaar, E. B. (Edward Bell), 1882-1966 | Landsteiner, Karl, 1868-1943 | Lectures | Lipschutz, Alexander, 1883-1980 | Loeb, Leo, 1869-1959 | LuckGe, Baldwin | MacNider, William de Berniere, 1881-1951 | McDermott, Walsh, 1909- | Medical sciences | Medicine -- Research | Medicine -- Research -- Finance | Medicine, Experimental | Mooser, Hermann | National Academy of Sciences, Washington, D.C. | New York Academy of Medicine | Nobel Prize | Osler, William, Sir, 1849-1919 | Pathology | Paul Ehrlich Stiftung | Photographs | Rockefeller Institute | Rogers, E. Stanfield | Rous, Peyton, 1879-1970 | Royal Society of Medicine Foundation. | Science publishing. | Shope, Richard E. (Richard Edwin) | Sloan-Kettering Institute for Cancer Research. | Smith, Frederick | Stanley, Wendell Meredith, 193 | TenBroeck, Carl, 1885-1966 | Viruses | Warthin, Aldred Scott, 1866-19 | Whipple, George Hoyt | World War, 1914-1918 -- Medical care | Wyckoff, Ralph W. G. (Ralph Walter Graystone) | Zinsser, Hans, 1878-1940



MANUSCRIPT COLLECTION

Dates:
1928-1989
Abstract:  

Thomas F. Anderson (1911-1991) was a biophysicist and electron microscopist whose research included Raman spectroscopy; the physiology of yeast; the biological effects of radiation; the biological applications of electron microscopy; and the genetics of bacteria, bacterial viruses, and bacteriophage. He was a Professor of Biophysics at the University of Pennsylvania and a Senior Member of the Institute for Cancer Research in Fox Chase.
Call #:  
Mss.Ms.Coll.75
Extent:
43 Linear feet
Subjects:  

American Association for the Advancement of Science | American Philosophical Society | Anderson, Andy, b. 1927 | Anderson, Thomas Foxen, 1911-1991 | Bacterial genetics | Bacterial genetics. | Bacteriophage and viral genetics | Bacteriophages | Bibliographical matters -- Schultz, Jack | Biochemistry and organic chemistry | Biographical and personal data -- Schultz, Jack | Biophysical Society | Biophysics | California Institute of Technology | Cancer, chemotherapy | Caspari, Ernst Wilhelm | Chance, Britton, 1913-2010 | Cold Spring Harbor Laboratory | Columbia University | Committee activities | Conferences and symposia | Congratulations, greetings, thanks -- Delbruck, Max. 60th birthday | Congratulations, greetings, thanks -- Horwitz Prize | Congratulations, greetings, thanks -- Pauling, Linus. 75th birthday | Crick, Francis, 1916-2004 | Crow, James F. | Cytogenetics | Demerec, M. (Milislav), 1895-1966 | Drosophila genetics | Electron Microscope Society of America | Electron microscopy | Fellowships, assistantships | Fellowships, assistantships -- Guggenheim | Genetics | Genetics Society of America | Gibbons, Ian R. (Ian Read), b. | Glass plate negatives | Hall, Cecil Edwin, b. 1912 | Hayes, William | Heidelberger, Michael | Hershey, A. D. (Alfred Day) | History of biology, especially genetics | Honors -- Horwitz Prize | Honors -- National Medal of Science | Human genetics | Institute for Medical Research | International Committee on Nomenclature of Viruses | International Union for Pure and Applied Biophysics | Invitations | Israel, Vance | Jacob, Francois, 1920-2013 | Kellenberger, Eduard | Kozinski, Andrzej W. | Laboratory notes | Laboratory techniques, equipment | Latarjet, Raymond | Lederberg, Joshua | Luria, Salvador Edward | Marine Biological Laboratory, Woods Hole | Metz, Charles W. | Mintz, Beatrice | Mirsky, Alfred Ezra | Molecular genetics | Monod, Jacques, 1910-1976 | Morgan, Thomas Hunt | Mudd, Stuart | National Academy of Sciences | National Cancer Institute (U.S.) | National Research Council (U.S.) | National Science Foundation, U.S. | Pauling, Linus, 1901-1994 | Philadelphia Electron Microscope Society | Photonegatives | Photoprints | Poetry and literature | Population genetics | Preservation of historical materials | Protozoan genetics | Publication | Publication -- Genetics | RCA Laboratories | Radiation -- Physiological effect | Radiation genetics | Raman spectroscopy | Recommendations | Referee's report | Requests for aid in finding positions | Richards, A. Glenn, Jr. | Schultz, Jack | Schultz, Jack,1904-1971. | Slides. | Smadel, Joseph E. (Joseph Edwi | Sonneborn, T. M. (Tracy Morton), 1905-1981 | Sonneborn, Tracy M. | Stanley, Wendell M. (Wendell Meredith), 1904-1971 | Statistics, biostatistics, biometrics | Stereographs | Teaching | The Institute for Cancer Resea | Travel -- Invitations, arrangements | U.S. Atomic Energy Commission | United States. National Institutes of Health | United States. Office of Naval Research | United States. Office of Scientific Research and Development | University of Pennsylvania. | Unpublished manuscripts, notes, etc. | Viral genetics | Walker, Donald H., Jr. | Wollman, Elie | Wulff, Peter | Wyckoff, Ralph W. G. (Ralph Walter Graystone) | Yost, Don M., b. 1893 | Zinder, Norton D.



MANUSCRIPT COLLECTION

Dates:
1891-1946
Abstract:  

Simon Flexner, born in 1863, one of the nation's leading experts in pathology and bacteriology, was most renowned for his research on cerebrospinal meningitis, polio and infantile paralysis. Arguably though, Flexner's stewardship of the Rockefeller Institute was his greatest contribution to medical and scientific research. His rise in the medical community began in the late nineteenth century in Louisville, Kentucky, where despite not having completed even the seventh grade, Flexner taught himself basic bacteriology by conducting experiments at home using a microscope borrowed from the pharmacy where he served as an apprentice. Granted a medical degree from the University of Louisville School of Medicine in 1889, he went on to a pathology fellowship at the newly opened John Hopkins School of Medicine. Within two short years of leaving Louisville, Flexner received an assistant of pathology appointment at Johns Hopkins. It was a quick ascent and the beginning of a long and brilliant career that included a prestigious appointment at the University of Pennsylvania and then a directorship at the new Rockefeller Institute where he realized his lifelong dream of creating a dynamic and productive research laboratory. The Rockefeller Institute became instantly famous worldwide as the preeminent research facility for virology and under Flexner's direction produced invaluable contributions in pathology, bacteriology, and immunology. This collection does not reflect the early phases of Flexner's career at Johns Hopkins but does document an early interest in meningitis and other infectious diseases with science-related correspondence, laboratory notebooks, and administrative correspondence with the New York City and State Departments of Health. There is abundant material on Flexner's directorship of the Rockefeller Institute for Medical Research, including Flexner's search for staff, an involved process which is detailed in correspondence with the scientists, many of whom became quite famous. Also included is material relating to the other institutions and Rockefeller philanthropies with which Flexner was involved. (Among the most significant correspondence, however, may be that which documents the support of the General Education Board and the Rockefeller Foundation in the development and subsequent reorganization of medical schools following brother Abraham Flexner's scathing report on medical education in the United States and Canada). This collection would be of great interest to anyone interested in the history of bacteriology, histology, and immunology or the general history of modern medicine and philanthropy.
Call #:  
Mss.B.F365
Extent:
115.5 Linear feet
Subjects:  

Cairns, Hugh, Sir, 1896-1952 | Cannon, Walter B. (Walter Bradford), 1871-1945 | Carrel, Alexis, 1873-1944 | Cohn, Alfred E. (Alfred Einstein), 1879-1957 | Cole, Rufus Ivory, 1872-1966 | Conklin, Edwin Grant, 1863-1952 | Councilman, W.T. (William Thom | Diaries. | Diseases | Education-United States | Epidemics -- United States | Flexner, Abraham, 1866-1959 | Flexner, Simon, 1863-1946 | Gelatin silver prints | Gowen, John Whittemore, 1893-1 | Immunology | Indians of North America -- Arizona | Indians of North America -- New Mexico | Landscape photographs | Lee, Frederic S. (Frederic Sch | Leishman, William B., Sir, 186 | Levene, P. A. (Phoebus Aaron), | Mall, Franklin P. (Franklin Pa | Medical education-United States | Medical sciences-United States | Medicine-United States | Meltzer, Samuel James, 1851-19 | Meningitis, Cerebrospinal-United States | Mirsky, Alfred E. | Navajo Indians | Noguchi, Hideyo, 1876-1928 | Olitsky, Peter K. | Opie, Eugene L. (Eugene Lindsay), 1873-1971 | Osborn, Henry Fairfield, 1857- | Osten, Anna L. von der | Papago Indian Reservation (Ariz.) | Pathology-United States | Poliomyelitis-United States | Portrait photographs | Public Health-United States | Rockefeller Foundation | Rockefeller Institute for Medical Research | Sabin, Albert B. (Albert Bruce) | Saddington, Ronald S. | Shaw, Edward B. | Shope, Richard E. (Richard Edwin) | Smith, Theobald, 1859-1934 | Spielmeyer, W. (Walther), b. 1 | Stewart, Walter B. | Stokes, Joseph (1896-1972) | Thomas, M. Carey (Martha Carey | Vallery-Radot, Pasteur, 1886 | Van Slyke, Donald Dexter, 1883-1971 | Veblen, Oswald, 1880-1960 | Wadsworth, Augustus Baldwin, 1 | Welch, William Henry, 1850-1934



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