The Amelia Susman Schultz Papers primarily contain original ethnographic fieldwork and related research at Round Valley Indian Reservation in California conducted during the late 1930s, especially with Konkow Maidu, Wailaki and Nomlaki Wintu people, and between 1948 and 1950 in Brienz, Switzerland. The papers include field notebooks, printed materials, research notes, one audio tape, draft manuscripts, sketch maps, and correspondence.

Apart from its importance for the study of Hale's personal and professional life, the collection is one of the richest sources for the history of science in the United States in the early twentieth century. It contains a good deal of significant material relating to the theoretical and instrumental development of astrophysics and the history of the Mount Wilson and Palomar Observatories. The collection is of singular importance for the study of science and government, particularly with respect to the affairs of the National Academy of Sciences and the National Research Council. It documents much of the early history of the California Institute of Technology. Finally, it contains substantial material on the general affairs of the scientific community in the United States and Europe [from Kevles 1968].

Britton Chance (1913-2010) was a biochemist and biophysicist as well as a pioneer in the field of biomedical optics. Chance received his Ph.D. in Physical Chemistry from the University of Pennsylvania in 1940 and his Ph.D. in Biology and Physiology from Cambridge University in 1942. Over the course of his nearly eight decade career, Chance was dedicated to the application and transfer of basic scientific research and technology to clinical medicine. The Britton Chance Papers contain correspondence, research notes, experimental data, publication materials, and photographs stemming from Chance's life as a biochemist, biophysicist, and yachtsman. The collection is broken up into fifteen series that document every aspect of his scientific work.