A pathologist and researcher at the Rockefeller Institute of Medical Research, 1914-1922, Harold Lindsay Amoss (1886-1956) specialized in research on infectious diseases ranging from poliomyelitis to meningitis, erysipelas, brucellosis, and encephalitis. The Amoss Papers are comprised primarily of materials relating to Harold Amoss' medical service in the United States Army during the First World War (1918-1919), to his research at the Rockefeller Institute of Medical Research, 1920-1922, and to his efforts to develop vaccines for meningitis and poliomyelitis.

Papers consist of letters, reports, addresses and lectures, relating to biological chemistry and other scientific topics, the Rockefeller Institute for Medical Research, refugee scientists, professional associations, etc.

The bacteriologist and virologist Thomas Milton Rivers spent over thirty years at the Rockefeller Institute as a researcher in the Department of Bacteriology and from 1937-1955, as Director. Working on measles and pneumonia, Rivers discovered the parainfluenzae bacillus and cultivated vaccine virus for human use, and during the 1950s, he played an important role in coordinating research on poliomyelitis as head of the National Institute for Infantile Paralysis. During the Second World War, Rivers led the Naval Medical Research Unit in the South Pacific, rising to the rank of Rear Admiral. The Rivers Papers contains correspondence, laboratory notes, speeches, and photographs documenting Rivers' activities at the Rockefeller Institute, the development of polio vaccine, and Rivers' Navy experience in the Pacific during World War II.

A physician and naturalist, Oswald Hope Robertson worked at the Rockefeller Institute, the Peking Union Medical College, and at the medical school of University of Chicago (1927-1951). With a broad range of research interests, Robertson contributed important work on the transmission of pneumonia, the disinfection of air with glycol vapors, and later in his career, on the physiology and ecology of salmonid fishes. He is best remembered, however, as the creator of the first blood bank, established for use by British and American forces during the First World War. The Robertson Papers contain correspondence, notes, articles, and notebooks on many of Robertson's major research interests, including his work on blood. His early work on salmonid ecology is represented in a journal and eleven notebooks stemming from fieldwork in the lakes of the Wind River Range in northwestern Wyoming, 1942-1951. There is also interesting material on the Research Corporation (New York City) concerning patents on glycol vapors and air sterilizers, as well as notes and manuscripts of papers on morphine experiments, canine pneumococcus, bacteremia, and the effects of hydrocortisone.

For his pioneering research on the link between viruses and cancer, the pathologist Francis Peyton Rous was awarded the Nobel Prize in Medicine in 1966. Working primarily at the Rockefeller Institute after 1909, Rous first came to notice for his theoretical construction of the first blood bank for use in France during World War I, a plan ultimately implemented by his assistant, Oswald H. Robertson. Subsequently, he left an important imprint on the development of experimental medicine, partly through his own research on the origins of cancer and his administrative activities at the Rockefeller, but also as editor of the Journal of Experimental Medicine from 1921-1970. The Rous Papers include correspondence, lectures, articles, reports, laboratory records, reprints, and photographs that document all aspects of the life and work of Peyton Rous. Reflecting his work at the Institute are letters of colleagues, information on assistants, and reports to the directors (1909-1959). Additional material relates to Rous' diverse organizational interests, including the American Cancer Society, Century Association, Jane Coffin Childs Memorial Fund for Medical Research (at Yale University), Federation of American Societies for Experimental Biology, Johns Hopkins University, National Academy of Sciences, National Research Council, New York Academy of Medicine, Royal Society of Medicine Foundation, and Sloan-Kettering Institute for Cancer Research.

Correspondence, notebooks, research data related to Cole's career as the first director at the Hospital of the Rockefeller Institute of Medical Research, 1908-1937. His research of pneumonia was conducted when the disease was epidemic. Personal correspondence reflect Cole's life as a medical resident at Johns Hopkins, 1899-1908. Documented are his memberships in leading medical organizations throughout his career, including the Association of American Physicians and the New York Academy of Medicine. This collection showcases the evolving changes in the medical profession from practicing physician to clinician.

A pathologist and cancer specialist, James B. Murphy (1884-1950) spent most of career associated with the Rockefeller Institute (1911-1950) investigating the role of lymphocytes in tuberculosis, x-ray mutagenesis, and the nature of malignant tumors in fowls. The Murphy Papers contains professional correspondence and research notes relating to James B. Murphy's cancer research at the Rockefeller, and information on several of the organizations to which he contributed or belonged, including the American Association for Cancer Research; American Bureau for Medical Aid to China; American Cancer Society; Bar Harbor Medical and Surgical Hospital; Roscoe B. Jackson Memorial Laboratory; Memorial Hospital for the Treatment of Cancer (New York City, ca. 1932-1950); National Advisory Cancer Council; and the New York Academy of Medicine (1923-1950). Murphy helped to develop mobile laboratories for hospitals in France during World War I.