A Sachem and Civil War adjutant to Ulysses Grant, Ely Samuel Parker was an important figure in the Seneca Indian nation during the first half of the nineteenth century. Trained as an engineer, Parker was deeply involved in the Senecas' land disputes with the Ogden Land Company and he played an important role in interpreting Seneca culture for a white audience, most notably as a consultant for Lewis Henry Morgan. Collected by Arthur C. Parker, the Ely Samuel Parker Papers include correspondence, manuscripts, and printed materials relating primarily to Seneca affairs, history, language, and culture, as well as politics, education, engineering, and the Civil War. Among Parker's correspondents were Henry Clay, Millard Fillmore, Henry M. Flagler, Lewis Henry Morgan, Henry Rowe Schoolcraft, Daniel Webster, and Asher Wright. Several letters relate to Parker's service as engineer of public buildings in Galena, Illinois, and to his Masonic activities. Among the noteworthy items in the collection are several essays on Seneca history and culture, a fragment of Parker's diary, 1847, and a significant quantity of material on the Seneca language assembled by Asher Wright.

The correspondence is principally to Zaccheus Collins (1810-1840), with bills, receipts, and notes on Rafinesque vs. Parker; letters from Collins, L.A. Tarascon, Lewis C. Beck, John Torrey, and Charles W. Short (1817-1835); and miscellaneous correspondence and documents relating to Rafinesque vs. Parker, with an account of the Felician Society of Feliciana County, Illinois (1820). The writings are chiefly on botanical topics, and include notes and essays on Indians, Blacks, grapes and wine-making, banking, and speculation. Rafinesque's growing interest in Indian antiquities, linguistics, and history is apparent in letters after 1820. There is an account of Rafinesque's scientific travels in North America and southern Europe (1800-1832), and a bibliography. The botanical notes include descriptions of specimens collected by Lewis and Clark, Patrick Gass, and Henry Muhlenberg.

Founded in 1743 by Benjamin Franklin, the American Philosophical Society was the first learned society in the United States. For over 250 years, the Society has played an important role in American cultural and intellectual life. Until the mid-nineteenth century, the Society fulfilled the role of a national academy of science, national library and museum, and even patent office. Early members of the Society included Thomas Jefferson, David Rittenhouse, Benjamin Rush, Stephen Peter Du Ponceau, George Washington, and many other figures prominent in American history. The Archives of the American Philosophical Society consists of 192.25 linear feet of material, organized into thirteen record groups dating back to 1743. The Society's archives extensively documents not only the organization's historical development but also its role in American history and the history of science and technology.