This microfilm contains letters and drafts of replies, memoranda, lists of plants and shrubs, observations on natural history, diary notes, extracts from reading, and recipes. There is a "Catalogue of Books given to [Friends] Publick School of Philadelphia" by Collinson dated 1749. There is a copy by Collinson of a May 16, 1560 note by Elizabeth I of a gift of old clothes to her maids of honor. A 1811 letter is from C. S. Collinson to Aylmer Bourke Lambert.

Reports on conferences and treaties with the Indians and miscellaneous Indian affairs in Pennsylvania, with emphasis upon the French and Indian War. Correspondents include: John Armstrong Thomas Barton Edward Braddock Daniel Claus George Croghan James Hamilton James Logan Hugh Mercer Andrew Montour Robert Hunter Morris Robert Orme Ferdinand J. Paris Thomas Penn Horatio Sharpe Joseph Shippen William Shirley John Stanwix Robert Stobo William Trent Conrad Weiser

The first volume includes extracts from the journals of Conrad Weiser and Christian Frederick Post (1757), Charles Thomson's "An Enquiry into the causes of the alienation of the Delaware and Shawanese Indians from the British interest" (1759), and a printed version of Judge Bradford's "Statement of facts and observations respecting the penal laws" (1792). The second volume contains selected letters and documents in the Pennsylvania state records on Indian relations, including transcriptions of several treaties between the Province of Pennsylvania and the Delawares and other Indians (1755-1758); the French and Indian War; and Braddock's campaign. Some manuscripts are written by Deborah Norris Logan and Charles Thomson.

These letters and papers include ten small volumes of letterbooks (1752-1781), and ca. 100 pieces of correspondence with Joseph Shippen (1750-1778). Topics discussed are business in Philadelphia and Lancaster, provincial politics, army supply in the French and Indian War, land purchases and speculation, housebuilding, and family affairs.