Correspondence and reports relating principally to medical research (tuberculosis, cancer, lymphatic system, pernicious anemia), writings and publications. There is material of note on the following organizations: American Association of Anatomists, American Association of University Women, American Woman's Association, Henry Strong Denison Medical Foundation, John Simon Guggenheim Memorial Foundation (re. fellowships), Hall of Fame for Great Americans, Institute for Advanced Study, Johns Hopkins School of Medicine, Medical Aid to China, Medical Aid to Spain, Naples Table Association (this existed to promote laboratory research by women); National Academy of Sciences, National Tuberculosis Association, Peking Union Medical College, Rockefeller Institute, Ellen Richards Prize (awarded by the Association to Aid Scientific Research by Women), Society for Experimental Biology and Medicine, University in Exile (i.e. New School for Social Research), White House Conference on Child Health and Protection, and the World Center for Women's Archives. There are abstracts and notes of unpublished scientific papers, and also materials for her biography of Franklin Paine Mall, 1934.

Mostly concerned with Blakeslee's studies on beans, blood groups, colchicine, Datura, embryo cultures, and horticulture. Many letters relate to the support and direction of the Smith College Genetics Experiment Station, which he headed. Other letters are about the Carnegie Institution of Washington, "Biological Abstracts," American Association for the Advancement of Science, American Philosophical Society, Institut de France, University of Connecticut. Also contains travel letters from Germany and miscellaneous lectures.