This journal was kept while Shippen was a student of medicine in London under Dr. Colin McKenzie and Dr. William Hunter. Notable people mentioned are Dennys De Berdt, Mark Akenside, George Whitefield, John Fothergill, David Garrick, and Thomas Penn.

The collection contains information on Fox family speculation in western lands, two manuscript maps from the 1790's and 1830's depicting the family's holdings in northwestern Pennsylvania, and a photograph album from the 1890's documenting Chestnutwold, the Fox estate adjacent to Andalusia. Chief correspondents are Samuel and George Fox.