The geneticist Milislav Demerec emigrated from Yugloslavia in 1919, spending nearly his entire career in the Department of Genetics at Cold Spring Harbor Laboratory. Working initially on the genetics of maize and later on Drosophila virilis, his research interests included radiation and chemical mutagenesis, and during the Second World War, penicillin and the genetics of antibiotic resistance. Demerec served as head of the laboratory at Cold Spring Harbor from 1941 until 1960. The Demerec collection contains the extant professional papers of Milislav Demerec, dating primarily from the time of his arrival at Cold Spring Harbor until his retirement. In addition to his correspondence with colleagues, the collection includes interesting material on the administration of Cold Spring Harbor laboratory during the 1940s and 1950s, data and research notes, material relating to professional organizations (e.g. Genetics Society of America, American Society of Naturalists), a lengthy series of lectures given by Demerec, and a large number of photographs pertaining to Demerec's research, but also to his colleagues and Cold Spring Harbor itself. There is also a Register of visitors to the laboratory (1927-1945) and a Milislav Demerec reprint list.

This is part of the large inventory for the American Philosophical Society Archives. For complete information concerning this collection, please view the Collection Description .

Though the Miscellaneous Manuscripts collection is composed of items that do not fall readily into any other existing collection, the two dominant intellectual areas represented in the collection are Early American History and History of Science.

4 reels. Correspondence of the Revolutionary War general from New York. Originals are at the New-York Historical Society.

This is part of the large inventory for the American Philosophical Society Archives. For complete information concerning this collection, please view the Collection Description .

The collection of about 850 items covers the period from 1782 to c. 1936, with the bulk dating to the 1780s to 1840s. The collection is divided into four series. Series I contains correspondence relating to a wide variety of topics, including French and English politics, business, trade, religious matters, and personal affairs. Many of the items are letters of introduction. There is also information on John Vaughan's immigration to America, Joseph Priestley, vaccines and inoculation (with Jefferson's comments on the same), Vaughan's business in Philadelphia, and the American Philosophical Society. Also included in this series are 2 boxes with copies of Vaughan correspondence as well as miscellaneous notes by E. W. Madeira, gathered in the course of his research on Vaughan in the 1930s. Series II consists of three volumes. Included are two of Vaughan's commonplace books. One, entitled, "J. Vaughan's book," May 17, 1779 (47 pp., in Latin; 870/L34), includes mostly Latin notations. The other commonplace book, dated 1783 (ca. 66 pp.; B V 462.c), includes comments on several prominent Americans, such as Benjamin Rush and David Rittenhouse, as well as American society generally. The third volume is a copybook with thirty letters spanning the period 1784 to 1801 (B V462.1). Series III includes material relating to Vaughan's administration of the estate of the Philadelphia merchant Samuel Merrick, 1796-1822 (Vaughan-Merrick Papers, B V462.m; 2 boxes). Series IV consists of correspondence between Vaughan and the DuPont Co. for which he served as agent (B V462.4; photocopies of 73 letters).

This is part of the large inventory for the American Philosophical Society Archives. For complete information concerning this collection, please view the Collection Description .

This is part of the large inventory for the American Philosophical Society Archives. For complete information concerning this collection, please view the Collection Description .

Simon Flexner, born in 1863, one of the nation's leading experts in pathology and bacteriology, was most renowned for his research on cerebrospinal meningitis, polio and infantile paralysis. Arguably though, Flexner's stewardship of the Rockefeller Institute was his greatest contribution to medical and scientific research. His rise in the medical community began in the late nineteenth century in Louisville, Kentucky, where despite not having completed even the seventh grade, Flexner taught himself basic bacteriology by conducting experiments at home using a microscope borrowed from the pharmacy where he served as an apprentice. Granted a medical degree from the University of Louisville School of Medicine in 1889, he went on to a pathology fellowship at the newly opened John Hopkins School of Medicine. Within two short years of leaving Louisville, Flexner received an assistant of pathology appointment at Johns Hopkins. It was a quick ascent and the beginning of a long and brilliant career that included a prestigious appointment at the University of Pennsylvania and then a directorship at the new Rockefeller Institute where he realized his lifelong dream of creating a dynamic and productive research laboratory. The Rockefeller Institute became instantly famous worldwide as the preeminent research facility for virology and under Flexner's direction produced invaluable contributions in pathology, bacteriology, and immunology. This collection does not reflect the early phases of Flexner's career at Johns Hopkins but does document an early interest in meningitis and other infectious diseases with science-related correspondence, laboratory notebooks, and administrative correspondence with the New York City and State Departments of Health. There is abundant material on Flexner's directorship of the Rockefeller Institute for Medical Research, including Flexner's search for staff, an involved process which is detailed in correspondence with the scientists, many of whom became quite famous. Also included is material relating to the other institutions and Rockefeller philanthropies with which Flexner was involved. (Among the most significant correspondence, however, may be that which documents the support of the General Education Board and the Rockefeller Foundation in the development and subsequent reorganization of medical schools following brother Abraham Flexner's scathing report on medical education in the United States and Canada). This collection would be of great interest to anyone interested in the history of bacteriology, histology, and immunology or the general history of modern medicine and philanthropy.

Bound with this is: Union Canal Company. Report of the President and Managers to the stockholders ... 1813-1814 -- New York. Citizens. Memorial ... in favor of a canal navigation ... -- New Jersey. Legislature. Report of the Commissioners ... for ... a canal ... -- New York (State). Legislature. Report ... on the subject of the canals, from Lake Erie to the Hudson River ... -- New York (State). Canal Commissioners. Report ... on the canals from Lake Erie to the Hudson River ... -- Granger, Gideon. Speech ... on the subject of a canal from Lake Erie to Hudson's River ... -- New York (State). Laws of the state of New York, respecting navigable communications ... -- Considerations on the Great Western Canal ... -- Say, Jean Baptiste. Des Canaux de navigation ... -- Stevens, John. Documents tending to prove the superior advantages of rail-ways ... -- Annesley, William. A description of [his] new system of naval architecture ...

Victor George Heiser, who was a preeminent public health physician, created a rich archive of material documenting all phases of his career, especially the international health work of the Rockefeller Foundation from 1915-1934. There are voluminous, detailed, and interesting diaries for the whole course of his adult life (1890-1972). There are notebooks reflecting on his early training and work (1890-1907), and lectures he attended at Jefferson Medical College in Philadelphia (1897).

Primary source materials for the history of quantum physics in the twentieth century, collected under the auspices of the American Philosophical Society and the American Physical Society, with a grant from the National Science Foundation.

This is part of the large inventory for the American Philosophical Society Archives. For complete information concerning this collection, please view the Collection Description .

This is part of the large inventory for the Benjamin Franklin Papers (Mss B F85). For complete information concerning this collection, please view the Collection Description .

This is a collection of letters, letterbooks, account books, scrapbooks, etc., concerning the families of Robert Hare and Thomas Willing. The letters and other documents include early family material, as well as documents written by numerous family relations, and some obviously only collected by them. The Willing family letters (1744-1901) are diverse, concerning family matters, business, society, comments on the Civil War, etc. There are numerous letters from Thomas Willing, many concerning his banking career, as President of the Bank of North America and later at the first Bank of the U.S. The Hare family letters (1724-1965) are more extensive and diverse, including much on travel in the U.S. and elsewhere. There is a letter from Robert Hare Jr. concerning steam engines, and letters from Horace Binney Hare concerning his education at Harvard, 1860, his trip to San Francisco and the west, 1862, and numerous letters written while a soldier in the Civil War. There are many letters from Horace Binney (1780-1875, DAB) to his daughter Esther, who was married to John Innes Clark Hare (1816-1905, DAB), concerning family travel and court cases. There are also letters from outside the family, such as those from Dorothea L. Dix. The bound volumes include, among others: Robert Hare letterbooks (1824-1825, 1841-1857), estate records, and laboratory expense accounts (1818-1860); G. H. Hare's journal or log of cruises aboard the U.S. United States (1841) and U.S. Flint (1845); Horace Binney Hare's 1862 journal of his trip to San Francisco. There are account books and accounts (1754-1795) kept by Thomas Willing; accounts of the controversy over the estate of John Innes Clark; and records of the First Colored Wesley Methodist Church of Philadelphia (receipt book, 1820-1848; minute book, 1827-1844). There are also Philadelphia court records, and minutes of the Common Council of the city, 1832.

This is part of the large inventory for the Benjamin Franklin Papers (Mss B F85). For complete information concerning this collection, please view the Collection Description .

2 reels. Diaries, letters, and anatomy commonplace book of the Massachusetts physician who served in the Continental Artillery during the Revolution. Originals are in the New York Public Library.

21 reels. Collection consists of correspondence, accounts, military records, land records, and other papers documenting the political and business activities and family affairs of Schuyler. Philip Schuyler was a Revolutionary War general and statesman, a prominent member of the landed gentry of New York, a delegate to the second Continental Congress, a member of the New York State Senate, and later a United States Senator. During the Revolutionary War he commanded the Continental Army forces of the Northern Dept. Originals are in the New York Public Library.