This small volume records excerpts from British natural philosophy and scientific journals, written sometime after 1799. It covers a wide range of subjects, from astronomy to zoology.

This commonplace book consists of brief writings and observations on agriculture, arts and manufactures, commerce, the army and navy, canals and roads, weights and measures, general politics, finance, and population. It includes a sketch of the Battle of Quebec groundworks and layout.

This volume contains medical notes by Wistar, including observations on yellow fever and arguments to prove its foreign origin, facts relative to the progress of the fever in 1797, the infection and death of Colonel Van Emburgh, the infection of the crew of the ship "Deborah" and of the Durham boat (1802), an account of the diseases which afflicted the family of James Hammar in Montgomery County (Pa.), facts relating to the typhus fever of 1812-1813, case histories (1796-1803), temperature chart (1758-1759, 1760), and a thermometrical journal (1760-1765) kept by Charles Norris and copied by Wistar from notes in possession of Joseph Parker Norris.

This item contains entries about prominent people (primarily accounts of their deaths); Philadelphia events and gossip; the Pennsylvania Hospital; questions for Meriwether Lewis on Indian physical history, medicine, morals, and religion; and his views on marriage, religion, physicians, etc. Also includes meeting with Captain Wells and Little Turtle; speculations on Indian skin color at the equator.