This volume is a finished manuscript copy, probably earlier than the "Westover Manuscripts," from which this varies slightly. Byrd interpolated into the narrative of his tour remarks on Indian customs, religion, warfare, and trade, in addition to observations on his Saponi guides. Several pages were added in 1817 in the hand of Nicholas Trist.

The first volume is minutes of the commissioners for determining the line between Pennsylvania and Maryland, which was copied by George M. Justine in 1842 from an "authenticated" copy owned by Ferdinand R. Hassler. The second volume contains receipts (62 items) for money spent by the Penn family for the survey.

An extensive family collection, the Vaux Family Papers center around the lives of George Vaux V (1721-1803), George Vaux VII (1779-1836), and George Vaux VIII (1832-1915), their business partners, siblings, wives, and children, and encompasses the extended Vaux family of Warders, Sansoms, Heads, Graffs, Morrises, Cressons, and Mayberrys. The collection includes correspondence, financial accounts, receipts, business records, journals, diaries, photographs, and legal documents.

James Burd (1726-1793) was well-known in colonial Pennsylvania through his role in the French and Indian War, as well as his connections to many of the colony's leading families (most notably the Shippen family). Initially starting out as a merchant in Philadelphia, Burd became increasingly involved with colonial affairs after moving to Lancaster County with his family in 1752. It would be on the frontier where Burd would make his mark first as a soldier, and later as a magistrate. The Burd-Shippen Papers consist mainly of letters and business documents sent to James Burd, with the bulk of the collection relating to the French and Indian War, 1754-1763, in which Burd served as an officer commanding troops at Fort Augusta and elsewhere. The collection reflects all aspects of Burd's life in Pennsylvania as a merchant, soldier, and magistrate; as well as his involvement with the Shippen family professionally and personally. Intermixed with items sent to Burd are receipts to his wife Sarah Shippen Burd, and correspondence between Edward Shippen and James Hamilton regarding land matters and Indian affairs in Lancaster.

Reports on conferences and treaties with the Indians and miscellaneous Indian affairs in Pennsylvania, with emphasis upon the French and Indian War. Correspondents include: John Armstrong Thomas Barton Edward Braddock Daniel Claus George Croghan James Hamilton James Logan Hugh Mercer Andrew Montour Robert Hunter Morris Robert Orme Ferdinand J. Paris Thomas Penn Horatio Sharpe Joseph Shippen William Shirley John Stanwix Robert Stobo William Trent Conrad Weiser