Jacob Hiltzheimer, farmer and assemblyman, emigrated from Germany to Philadelphia in 1748 and lead a moderately active political and social life. He was a successful farmer and raised select livestock in the city of Philadelphia. He also boarded horses including those of John Penn and George Washington. He served in the Pennsylvania Assembly for 11 consecutive years beginning in 1786. He was an active contributor in civil affairs and took a remarkable enthusiastic interest in events, in persons, and in every day life all of which he wrote down in his diary. As a result of his Revolutionary War and political acquaintances his contacts were numerous. Hiltzheimer's record of social affairs are for the most part routine daily events such as buying and trading horses, attending barbecues and funerals, and drinking punch. However it is his every day accounts that also records significant events such as the Revolutionary War, transactions of the Pennsylvania Assembly, and Philadelphia's yellow fever epidemics, as well as the dealings of significant people including George Washington, Thomas Mifflin, and John Hancock.

This journal was kept while Shippen was a student of medicine in London under Dr. Colin McKenzie and Dr. William Hunter. Notable people mentioned are Dennys De Berdt, Mark Akenside, George Whitefield, John Fothergill, David Garrick, and Thomas Penn.

This autobiography relates Rush's experiences in college and medical school; his meetings with notable doctors; his life in Scotland, England, and France; his medical views; the military and politics during the Revolutionary War; and brief sketches of personalities of that period.

This item contains entries about prominent people (primarily accounts of their deaths); Philadelphia events and gossip; the Pennsylvania Hospital; questions for Meriwether Lewis on Indian physical history, medicine, morals, and religion; and his views on marriage, religion, physicians, etc. Also includes meeting with Captain Wells and Little Turtle; speculations on Indian skin color at the equator.

The collection contains information on Fox family speculation in western lands, two manuscript maps from the 1790's and 1830's depicting the family's holdings in northwestern Pennsylvania, and a photograph album from the 1890's documenting Chestnutwold, the Fox estate adjacent to Andalusia. Chief correspondents are Samuel and George Fox.