This volume contains letters relating to the purchase and shipment of goods in America, Europe, and the West Indies, commecing 22d, 12mo. 1744, ending 6th, 2mo. 1747. Some are signed by Matthias Aspden, John Reynell, and John Smith.

The collection includes letters between Hutchinson and his uncle Israel Pemberton, written while Hutchinson was a student of medicine in London. There are also 12 tickets of admission to medical lectures in Philadelphia and London, including one given by William Hunter, and 3 unused cards of admission to Hutchinson's own lectures. Miscellaneous items include Hutchinson's marriage certificate; genealogical data on the Hutchinson, Hare, and Pemberton families; and stock certificates, 1857-1872, of the McKean and Elk Land and Improvement Company. Materials dated post-1793 are to and from Hutchinson family members.