This collection contains minutes of the Society, 1781-1975; minutes of the directors of the Corporation, 1929-1947; membership book (with signatures of early members), 1785; and names of later members. There are also deeds to the meeting house and burying ground; treasurers' accounts; reports of officers and committees; bills and receipts for constructing, maintaining, and repairing the meeting house; cancelled checks; and letters to the Society and its officers, especially Samuel Wetherill, 1883-1884.

This collection includes letters, diaries, notebooks, and early photographs, relating primarily to the Wister family of Germantown and Philadelphia. Much of the correspondence concerns domestic news and consists of letters from or to Sarah Wister. These include interesting observations on Germantown and Philadelphia society from other families as well, such as the Bayntons and Bullocks. There are numerous letters from various Wisters, including Casper, Charles Jones, Elizabeth (including a journal of a trip to Bristol, 1783), Hannah, John, Owen Jones, and others. There is also poetry by Sarah.